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537-05-3

537-05-3结构式
537-05-3结构式
  • 常用中文名:茴胍卡因
  • 常用英文名:Guanicaine
  • CAS号:537-05-3
  • 分子式:C23H26ClN3O3
  • 分子量:427.92400
  • 发布时间:2018-08-05 19:23:24
  • 更新时间:2024-01-31 12:01:22

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中文名 茴胍卡因
英文名 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine,hydrochloride
英文别名 Guanicaine
Acoin
Diparaanisyl-monophenethyl-guanidin-hydrochlorid [German]
2-(4-Ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine hydrochloride
Dianisyl-monophenethylguanidine hydrochloride
Akoin hydrochlorid [German]
Phenodianisyl
Phenodianisyl hydrochloride
Acoine
Acoin hydrochloride
沸点 545.9ºC at 760mmHg
分子式 C23H26ClN3O3
分子量 427.92400
闪点 284ºC
精确质量 427.16600
PSA 64.11000
LogP 6.26220

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MF2000000
CHEMICAL NAME :
Guanidine, 2-(p-ethoxyphenyl)-1,3-bis(p-methoxyphenyl)-, hydrochloride
CAS REGISTRY NUMBER :
537-05-3
LAST UPDATED :
199012
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C23-H25-N3-O3.Cl-H
MOLECULAR WEIGHT :
427.97

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
HDTU** "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933 Volume(issue)/page/year: -,-,1933
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
53 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
REFERENCE :
WDMU** "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936 Volume(issue)/page/year: -,-,1936
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1291,1935
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MEIEDD Merck Index. (Merck & Co., Inc., Rahway, NJ 07065) 10th ed. 1983. For publisher information, see 85KYAH. Volume(issue)/page/year: 10,1043,1983
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1291,1935

海关编码 2925290090
海关编码 2925290090
中文概述 2925290090 其他亚胺及其衍生物,以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素 品名, 成分含量, 用途
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%