173833-08-4

• 常用中文名：pTH (1-31) amide (human)
• 常用英文名：pTH (1-31) amide (human)
• CAS号：173833-08-4
• 分子式：C₁₆₂H₂₇₀N₅₀O₄₆S₂
• 分子量：
• 相关类别： 研究领域 代谢疾病
• 发布时间：2018-06-07 08:06:41
• 更新时间：2024-02-29 13:38:46
• 人PTH-(1-31)酰胺是一种PTH类似物。人PTH-(1-31)酰胺刺激磷脂酰胆碱水解并刺激腺苷酸环化酶释放[1]。

名称

• 英文名: (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxy-propanoyl]amino]-3-methyl-butanoyl]amino]-3-hydroxy-propanoyl]amino]-4-carboxy-butanoyl]amino]-3-methyl-pentanoyl]amino]-5-oxo-pentanoyl]amino]-4-methyl-pentanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-oxo-butanoyl]amino]-4-methyl-pentanoyl]amino]acetyl]amino]hexanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-3-hydroxy-propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-5-[[(1S)-1-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-1-[[(1S)-1-[[(1S)-5-amino-1-[[(1S)-5-amino-1-[[(1S)-1-[[(1S)-4-amino-1-[[(1S)-2-[[(1S)-1-carbamoyl-2-methyl-propyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-4-oxo-butyl]carbamoyl]-3-methyl-butyl]carbamoyl]pentyl]carbamoyl]pentyl]carbamoyl]-4-guanidino-butyl]carbamoyl]-3-methyl-butyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-carboxy-propyl]carbamoyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-5-oxo-pentanoic acid

物化性质

• 分子式: C₁₆₂H₂₇₀N₅₀O₄₆S₂

生物活性

• 描述: 人PTH-(1-31)酰胺是一种PTH类似物。人PTH-(1-31)酰胺刺激磷脂酰胆碱水解并刺激腺苷酸环化酶释放[1]。
• 相关类别:
  信号通路 >> 其他 >> 甲状腺激素受体
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Singh AT, et al. Parathyroid hormone (PTH)-(1-34), [Nle(8,18),Tyr34]PTH-(3-34) amide, PTH-(1-31) amide, and PTH-related peptide-(1-34) stimulate phosphatidylcholine hydrolysis in UMR-106 osteoblastic cells: comparison with effects of phorbol 12,13-dibutyrate. Endocrinology. 1999 Jan;140(1):131-7.