70-38-2

• 常用中文名：苄菊酯
• 常用英文名：Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (2,4-dimethylphenyl)methylester
• CAS号：70-38-2
• 分子式：C₁₉H₂₆O₂
• 分子量：286.40900
• 相关类别： 研究领域 其他
• 发布时间：2018-06-14 16:11:09
• 更新时间：2024-01-11 19:48:45
• Dimethrin是一种拟除虫菊酯类杀虫剂。

名称

• 中文名: 苄菊酯
• 英文名: dimethrin
• 英文别名: Dimethrin [ANSI]; 2,4-dimethylbenzyl (1RS,3RS; Dimetrin; Caswell No. 359; DIMETHRIN; 2,4-Dimethylbenzylchrysanthemumate; (2,4-dimethylphenyl)methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate; Dimethrine; (2,4-dimethylphenyl)methyl (1Ξ,3Ξ)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate; 1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; (2,4-dimethylphenyl)methyl 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate; 2,4-dimethylbenzyl (1RS)-cis-trans-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; 2,4-dimethylbenzyl (±)-cis-trans-chrysanthemate

物化性质

• 密度: 1.042g/cm3
• 沸点: 363.9ºC at 760 mmHg
• 分子式: C₁₉H₂₆O₂
• 分子量: 286.40900
• 闪点: 167.8ºC
• 精确质量: 286.19300
• PSA: 26.30000
• LogP: 4.58500
• 折射率: 1.557
• 储存条件:

  库房通风低温干燥; 与食品原料分开储运

• 分子结构:

  1、 摩尔折射率：88.46

  2、 摩尔体积（cm³/mol）：274.7

  3、 等张比容（90.2K）：693.0

  4、 表面张力（dyne/cm）：40.4

  5、 介电常数（F/m）：

  6、 偶极距（D）：

  7、 极化率（10^-24cm³）：35.07

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:2

  4.可旋转化学键数量:5

  5.互变异构体数量:无

  6.拓扑分子极性表面积26.3

  7.重原子数量:21

  8.表面电荷:0

  9.复杂度:417

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:2

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

生物活性

• 描述: Dimethrin是一种拟除虫菊酯类杀虫剂。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. M S MASRI, et al. METABOLIC FATE OF TWO CHRYSANTHEMUMIC ACID ESTERS: BARTHRIN AND DIMETHRIN. Toxicol Appl Pharmacol. 1964 Nov:6:711-5.

毒性和生态

毒理学数据: 口服- 大鼠 LD50: 40000 毫克/ 公斤; 口服- 小鼠 LD50: 10000 毫克/ 公斤 CHEMICAL IDENTIFICATION RTECS NUMBER : GZ1455000 CHEMICAL NAME : Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, 2,4-dimethylbenzyl ester CAS REGISTRY NUMBER : 70-38-2 LAST UPDATED : 199701 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C19-H26-O2 MOLECULAR WEIGHT : 286.45 WISWESSER LINE NOTATION : L3TJ A1 A1 BVO1R B1 D1& C1UY1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 40 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 5,79,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 gm/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - convulsions or effect on seizure threshold Blood - other changes REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(5),116,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >15 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,5,1978 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >4900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,112,1964 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : >9800 mg/kg TOXIC EFFECTS : Behavioral - food intake (animal) Behavioral - fluid intake REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,112,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 182 gm/kg/52W-C TOXIC EFFECTS : Liver - changes in liver weight REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,112,1964 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 57 gm/kg/16W-C TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,716,1964

安全

• 危险品运输编码: UN 3082
• 包装等级: III