81-77-6

• 常用中文名：颜料蓝60
• 常用英文名：Vat Blue 4
• CAS号：81-77-6
• 分子式：C₂₈H₁₄N₂O₄
• 分子量：442.42200
• 相关类别： 染料及颜料 染料 还原染料
• 发布时间：2018-09-02 13:33:28
• 更新时间：2024-01-06 17:17:14

• 1、还原蓝RSN 主要用于棉纤维染色及棉布印花，也用于维棉、涤棉织物的两浴套染。染黏胶纤维得色较浅。可与还原蓝、棕、橄榄等拼蓝色、深灰等。也用于制造油墨用颜料。

  2、广泛用于纱线的隐色体染色，超细粉末可用于棉布及涤/棉的悬浮轨染，也用于麻、粘纤、维纶及纤维及其织物的染色印花。还用于粘棉、维棉混纺织物及锦纶染色。应用本品印染的织物经脲醛、氰醛、DMEU或2D树脂整理，色光变化极微。如用BHES树脂整理后，则色光变绿与暗。

名称

• 中文名: 颜料蓝60
• 英文名: Vat Blue 4
• 中文别名: 还原蓝 4; 还原蓝RS; 6,15-二氢二蒽并哒嗪-5,9,14,18-四酮; 颜料蓝 GR; 还原蓝RD; 还原蓝RD; 阴丹士林蓝; 蒽醌蓝; 阴丹酮; 颜料蓝 60; 阴丹酮
• 英文别名: blueo; indanthrone; Blue 60; e130; vat; c.i.1106; ponsolrp; foodblue4; vatblueod; l-blau1; Pigment Blue 60; anthraquinone blue; EINECS 201-375-5; vatblueo; indanthrene; 6,15-dihydroanthrazine-5,9,14,18-tetrone

物化性质

• 密度: 1.487 g/cm3
• 沸点: 740.2ºC at 760 mmHg
• 熔点: 470-500°C
• 分子式: C₂₈H₁₄N₂O₄
• 分子量: 442.42200
• 闪点: 253.9ºC
• 精确质量: 442.09500
• PSA: 99.86000
• LogP: 4.14060
• 外观性状: 蓝色针状,带有一种金属光泽
• 折射率: 1.746
• 储存条件:

  密封于阴凉处保存。

• 稳定性: Incompatible with strong oxidizing agents.
• 水溶解性: 水溶性：不溶；可溶于：硫酸；不溶：醇,乙醚
• 分子结构:

  1、 摩尔折射率：120.71

  2、 摩尔体积（cm³/mol）：297.4

  3、 等张比容（90.2K）：859.7

  4、 表面张力（dyne/cm）：69.8

  5、 极化率（10^-24cm³）：47.85

• 计算化学:

  1.疏水参数计算参考值（XlogP）:4.9

  2.氢键供体数量:2

  3.氢键受体数量:6

  4.可旋转化学键数量:0

  5.互变异构体数量:28

  6.拓扑分子极性表面积92.3

  7.重原子数量:34

  8.表面电荷:0

  9.复杂度:857

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：深蓝色粉末

  2. 密度（g/mL,25/4℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：不溶于水、乙酸、乙醇、吡啶、二甲苯、甲苯，微溶于氯仿 (热)、邻氯苯酚、喹啉。于浓硫酸中呈棕色，稀释后产生蓝色沉淀。于保险粉碱性溶液中呈蓝色，于酸性液中呈红光蓝色。

MSDS

Section I.Chemical Product and Company Identification Chemical Name Indanthrone Portland OR SynonymC.I. Pigment Blue 60, Cl. 69800 Chemical FormulaC28H14N2O4 CAS Number81-77-6 Section II.Composition and Information on Ingredients Chemical NameCAS Number Percent (%)TLV/PELToxicology Data Indanthrone81-77-6--------- Not available.Rat LD50 (oral) 2000mg/kg Section III. Hazards Identification Acute Health EffectsNo specific information is available in our data base regarding the toxic effects of this material for humans. However, exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. CARCINOGENIC EFFECTS : Not available. Chronic Health Effects MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. Toxicity to the reproductive system: Not available. There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Section IV.First Aid Measures Eye ContactCheck for and remove any contact lenses. DO NOT use an eye ointment. Flush eyes with running water for a minimum of 15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and supportively. Skin Contact If the chemical gets spilled on a clothed portion of the body, remove the contaminated clothes as quickly as possible, protecting your own hands and body. Place the victim under a deluge shower. If the chemical touches the victim's exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. Seek medical attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing. InhalationIf the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered. Seek medical attention. Treat symptomatically and supportively. IngestionRemove dentures if any. Have conscious person drink several glasses of water or milk. INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. NEVER give an unconscious person anything to ingest. Seek medical attention. Treat symptomatically and supportively. Section V. Fire and Explosion Data Not available. FlammabilityCombustible.Auto-Ignition Flammable Limits Flash PointsNot available. Not available. Combustion ProductsThese products are toxic carbon oxides (CO, CO 2), nitrogen oxides (NO, NO2). Fire Hazards No specific information is available regarding the flammability of this compound in the presence of various materials. Explosion HazardsRisks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. No additional information is available regarding the risks of explosion. Fire Fighting Media SMALL FIRE: Use DRY chemicals, CO 2, water spray or foam. and InstructionsLARGE FIRE: Use water spray, fog or foam. DO NOT use water jet. Continued on Next Page Indanthrone Section VI.Accidental Release Measures Spill CleanupIn case of a spill and/or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a Instructionsshovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on disposal. DSD/Pictogra Handling and Storage Handling and StorageKeep away from heat and sources of ignition. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. DO NOT breathe dust. In case of insufficient ventilation, Information wear suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible. Treat symptomatically and supportively. Avoid contact with skin and eyes. Always store away from incompatible compounds such as oxidizing agents. Section VIII. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSplash goggles. Lab coat. Dust respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section IX. Physical and Chemical Properties Solubility Physical state @ 20°CPowder.Insoluble in cold water, hot water, methanol, diethyl ether, acetone. Not available. Specific Gravity Molecular Weight442.43Partition CoefficientNot available. Boiling PointNot available.Vapor PressureNot available. Melting PointNot available.Vapor DensityNot available. Not available.VolatilityNot available. Refractive Index Critical TemperatureOdorNot available. Not available. ViscosityNot available.TasteNot available. Section X.Stability and Reactivity Data Stability This material is stable if stored under proper conditions. (See Section VII for instructions) Conditions of Instability Avoid excessive heat and light. Incompatibilities Reactive with strong oxidizing agents. Section XI. Toxicological Information RTECS NumberCB8761100 Routes of ExposureEye contact. Ingestion. Inhalation. Rat LD50 (oral) 2000mg/kg Toxicity Data Chronic Toxic EffectsCARCINOGENIC EFFECTS : Not available. MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. Toxicity to the reproductive system: Not available. There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Acute Toxic EffectsNo specific information is available in our data base regarding the toxic effects of this material for humans. However, exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. Continued on Next Page Indanthrone Section XII.Ecological Information EcotoxicityNot available. Environmental FateNot available. Section XIII. Disposal Considerations Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with Waste Disposal a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state, and local regulations when disposing of this substance. Section XIV. Transport Information DOT ClassificationNot a DOT controlled material (United States). PIN NumberNot available. Proper Shipping Name Not available. Packing Group (PG)Not available. DOT Pictograms Section XV. Other Regulatory Information and Pictograms TSCA Chemical InventoryThis product is ON the EPA Toxic substances control act (TSCA) inventory. (EPA) WHMIS Classification Not controlled under WHMIS (Canada). (Canada) EINECS Number (EEC) Not available. EEC Risk StatementsNot available. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 1、急性毒性 大鼠口径LD:2 mg/kg；大鼠气管LD50: 250 mg/kg； CHEMICAL IDENTIFICATION RTECS NUMBER : CB8761100 CHEMICAL NAME : 5,9,14,18-Anthrazinetetrone, 6,15-dihydro- CAS REGISTRY NUMBER : 81-77-6 BEILSTEIN REFERENCE NO. : 0367131 LAST UPDATED : 199710 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C28-H14-N2-O4 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 38B,60,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intratracheal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1327,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4604 No. of Facilities: 79 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 563 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4604 No. of Facilities: 86 (estimated) No. of Industries: 5 No. of Occupations: 8 No. of Employees: 22663 (estimated) No. of Female Employees: 16700 (estimated)

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): 22-36/37/39
• RTECS号: CB8761100
• 海关编码: 3204170000

合成路线

上下游产品

上游产品  10
82-45-1 24044-24-4 117-79-3 60245-50-3
5702-54-5 91-20-3 82-27-9 3300-23-0
86-57-7 6374-73-8
下游产品  2
130-20-1 6259-70-7

制备

方法 1：熔融法。
以 2-氨基蒽醌为原料，经与温合碱碱熔后，用保险粉溶液精制得产物。或以 2-氨基蒽醌为原料，二甲亚砜为溶剂，与氢氧化钾进行碱熔反应，再经保险粉溶液精制后得产物。。
在缩合锅中加入无水混合碱 595kg (氢氧化钾占 68%)，加热熔融后，加入 131kg 乙酸钠 (98%)、1.5kg 油酸 (工业品)。关闭缩合锅，加热至 185-190℃，同时用氮气驱赶空气，使反应液处于氮气保护下，于 30min 内加入 263kg 2-氨基蒽醌，控制温度不超过 215℃，加毕保温 1h，再加入 25kg 亚硝酸钠 (98%)，控制温度不超过 230℃，约 2h 内加完。继续搅拌 20min，完成碱熔反应。
在精制锅中放入 5000L 水，通入氮气驱赶空气，放入碱熔物料，搅拌 2h；降温至 51℃左右，加入 110kg 保险粉，慢速搅拌，降温至 45℃时，结晶析出。过滤，滤饼用保险粉水溶液洗涤 (洗涤水由 20L 液碱、20kg 保险粉、5000L 水配制而成)，再用 45℃温水洗至滤液呈微蓝，抽干，得染料隐色体湿料。
在打浆机中加入染料隐色体湿料，适量水打浆，并通入空气于 60℃氧化 6h 后，加入扩散剂 NNO 150kg 进行砂磨，喷雾干燥得成品。每批约 138kg (100%)。

方法 2：溶剂法。
在缩合锅中加入 15L 二甲亚砜、6.802kg 2-氨基蒽醌，于 1h 左右升温至 132℃，待 2-氨基蒽醌基本溶解，继续升温至 130-150℃维持 30min，使其完全溶解。此时停止加热，通入空气，温度约下降至 128℃，于 10min 内加入 4.4L 氢氧化钾溶液 (39.8%)。并继续通入空气，于 (125±2)℃保温反应 4h。然后加水 20L，物料温度降至 80℃左右过滤，用 50-60℃的水 40L 洗缩合锅，并用其洗滤饼，抽干。
在精制锅中加入 380L 水，上述滤饼打浆 1h，加碱 27kg (43%氢氧化钠)，升温至 56-57℃，加入 5.44kg 保险粉 (85%)，保持温度 20min，再于 40min 内降温至 52℃，结晶析出，过滤，滤饼用 50℃左右洗涤水 [410L 水、5.8kg 氢氧化钠 (43%)、0.82kg 保险粉 (85%) 配制] 洗涤，再用清水洗涤抽干。
在酸化锅中加水 100L，加入精制滤饼，打浆 2h，加水调体积至 200L，加硫酸调 pH 值为 2-3 (约用 12.34%的硫酸 10kg)。搅拌 20min 过滤，用水洗至中性，吹干。进行砂磨即得成品。

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%