405-79-8

• 常用中文名：4-氟苯氧乙酸
• 常用英文名：4-fluorophenoxyacetic acid
• CAS号：405-79-8
• 分子式：C₈H₇FO₃
• 分子量：170.138
• 相关类别： 化学试剂 有机试剂 脂肪酸
• 发布时间：2018-05-08 08:00:00
• 更新时间：2024-01-03 15:57:18
• 4-Fluorophenoxyacetic acid (4FPA) 可诱导单性结实。4-Fluorophenoxyacetic acid (4FPA) 可保护谷物免受吸虫的侵害从而提高田间水稻产量。

名称

• 中文名: 4-氟苯氧乙酸
• 英文名: 4-Fluorophenoxyacetic acid
• 中文别名: 对氟苯氧乙酸
• 英文别名: 4-fluorophenoxyacetic acid; Acetic acid, 2-(4-fluorophenoxy)-; 2-(4-Fluorophenoxy)acetic acid; EINECS 206-974-5; Acetic acid, (4-fluorophenoxy)-; (4-Fluorophenoxy)acetic acid; MFCD00004304

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 295.2±15.0 °C at 760 mmHg
• 熔点: 104-104.5 °C(lit.)
• 分子式: C₈H₇FO₃
• 分子量: 170.138
• 闪点: 132.4±20.4 °C
• 精确质量: 170.037918
• PSA: 46.53000
• LogP: 1.47
• 外观性状: 白色至淡米色结晶粉末
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.520
• 储存条件: 室温，干燥
• 分子结构:

  1、 摩尔折射率：39.12

  2、 摩尔体积（m³/mol）：128.7

  3、 等张比容（90.2K）：332.6

  4、 表面张力（dyne/cm）：44.5

  5、 极化率（10 ^-24cm ³）：15.50

• 更多:

  一、物性数据

  性状：不可用

  密度（g/mL,25/4℃）：不可用

  相对蒸汽密度（g/mL,空气=1）：不可用

  熔点（ºC）： 104-105 沸点（ºC,常压）： 不可用

  沸点（ºC,5.2kPa）：不可用

  折射率：不可用

  闪点（ºC）：不可用

  比旋光度（º）：不可用

  自燃点或引燃温度（ºC）：不可用

  蒸气压（kPa,25ºC）：不可用

  饱和蒸气压（kPa,60ºC）：不可用

  燃烧热（KJ/mol）：不可用

  临界温度（ºC）：不可用

  临界压力（KPa）：不可用

  油水（辛醇/水）分配系数的对数值：不可用

  爆炸上限（%,V/V）：不可用

  爆炸下限（%,V/V）：不可用

  溶解性：不可用

生物活性

• 描述: 4-Fluorophenoxyacetic acid (4FPA) 可诱导单性结实。4-Fluorophenoxyacetic acid (4FPA) 可保护谷物免受吸虫的侵害从而提高田间水稻产量。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Burton R. Anderson. et al. Control of Annual Bluegrass and Crabgrass in Turf with Fluorophenoxyacetic Acids. Weed Science. January 1958 , pp. 52-58.

  [2]. Wanwan Wang, et al. Induction of Defense in Cereals by 4-fluorophenoxyacetic Acid Suppresses Insect Pest Populations and Increases Crop Yields in the Field. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12017-12028.

MSDS

Name: 4-Fluorophenoxyacetic acid 99+% Material Safety Data Sheet Synonym: None CAS: 405-79-8 Section 1 - Chemical Product MSDS Name:4-Fluorophenoxyacetic acid 99+% Material Safety Data Sheet Synonym:None Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 405-79-8 4-Fluorophenoxyacetic acid 99+ 206-974-5 Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 405-79-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: white Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 104.00 - 104.50 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Not available. Specific Gravity/Density: Not available. Molecular Formula: C8H7FO3 Molecular Weight: 170.14 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride gas. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 405-79-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Fluorophenoxyacetic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 405-79-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 405-79-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 405-79-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 二、毒理学数据： 急性毒性：不可用。 生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。

安全

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R22;R36/37/38
• 安全声明 (欧洲): S37/39-S26
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3
• 海关编码: 2918990090

合成路线

777-87-7 ~% 405-79-8

文献：Chevron Research Company Patent: US4620867 A1, 1986 ;

371-41-5 79-11-8 ~63% 405-79-8

文献：Heescher, Carolin; Schollmeyer, Dieter; Nubbemeyer, Udo European Journal of Organic Chemistry, 2013 , # 20 p. 4399 - 4404

371-41-5 ~% 405-79-8

文献：Xia, Yan; Won, Misun; Kang, Jung Eun; Park, Song-Kyu; Lee, Kiho; Kim, Hwan-Mook; Lee, Kyeong Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 12 p. 3826 - 3829

371-41-5 105-36-2 ~69% 405-79-8

文献：Chen, Ting; Shen, Ping; Li, Yanjun; He, Hongwu Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 9 p. 2135 - 2145

459-60-9 ~% 405-79-8

文献：Suter; Lawson; Smith Journal of the American Chemical Society, 1939 , vol. 61, p. 161,164

459-26-7 ~% 405-79-8

文献：Suter; Lawson; Smith Journal of the American Chemical Society, 1939 , vol. 61, p. 161,164

55444-93-4 ~% 405-79-8

文献：Gurumurthy, R.; Balakrishnan, N. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 2 p. 154 - 156

32376-34-4 79-11-8 ~% 405-79-8

文献：Molenaar-Langeveld, Tineke A.; Ingemann, Steen; Nibbering, Nico M. M. Organic Mass Spectrometry, 1993 , vol. 28, # 10 p. 1167 - 1178

上下游产品

上游产品  8
777-87-7 371-41-5 79-11-8 105-36-2
459-60-9 459-26-7 55444-93-4 32376-34-4
下游产品  10
1426-73-9 405-78-7 399-41-7 398-63-0
371-41-5 50-00-0 201230-82-2 2924-66-5
332-50-3 777-87-7

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%