632-99-5

• 常用中文名：碱性品红
• 常用英文名：Fuchsine base monohydrochloride
• CAS号：632-99-5
• 分子式：C₂₀H₂₀ClN₃
• 分子量：337.846
• 相关类别： 染料及颜料 染料 碱性染料
• 发布时间：2018-04-04 08:00:00
• 更新时间：2024-01-02 10:42:11
• Fuchsine base (monohydrochloride) 是一种品红染料,经验证可用于石碳酸-品红的抗酸染色。

名称

• 中文名: 碱性品红
• 英文名: rosanilin
• 中文别名: 碱性紫14; 玫瑰苯胺盐酸盐; 盐基品红; 碱性新品红
• 英文别名: C.I. Basic Violet 14; Basic magenta; Basic fuchsine; Fuchsine; Benzenamine, 4-[(4-aminophenyl)(4-imino-2,5-cyclohexadien-1-ylidene)methyl]-2-methyl-, hydrochloride (1:1); 4-[(4-aminophenyl)-(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]aniline,hydrochloride; Basic violet 14; Rosaniline hydrochloride; Fuchsin basic; MFCD00012569; EINECS 211-189-6; magenta powder; Rosaniline chloride; 4-[(4-Aminophenyl)(4-imino-2,5-cyclohexadien-1-ylidene)methyl]-2-methylaniline hydrochloride (1:1); MAGENTA; Fuchsin; Rosaniline

物化性质

• 密度: 0.999 g/mL at 20 °C
• 沸点: 589.3ºC at 760 mmHg
• 熔点: 250 °C
• 分子式: C₂₀H₂₀ClN₃
• 分子量: 337.846
• 闪点: 48 °F
• 精确质量: 337.134583
• PSA: 75.89000
• LogP: 6.17120
• 外观性状: 黄色至绿色粉末
• 折射率: n20/D 1.334
• 储存条件:

  存放在密封容器内，并放在阴凉，干燥处。储存的地方必须远离氧化剂。

• 稳定性:

  远离氧化物。

• 水溶解性: 4 G/L (25 ºC)
• 分子结构:

  1、 摩尔折射率：92.63

  2、 摩尔体积（cm³/mol）：258.4

  3、 等张比容（90.2K）：676.1

  4、 表面张力（dyne/cm）：46.8

  5、 极化率（10^-24cm³）：36.72

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:4

  3.氢键受体数量:3

  4.可旋转化学键数量:2

  5.互变异构体数量:7

  6.拓扑分子极性表面积75.9

  7.重原子数量:24

  8.表面电荷:0

  9.复杂度:515

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

• 更多:

  1. 性状：深绿色结晶性粉末。

  2. 密度（g/mL,25/4℃）：0.999

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：250

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）：未确定

  7. 折射率：1.334

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：微溶于水，水溶液呈红色。溶于乙醇和戊醇，不溶于醚。

生物活性

• 描述: Fuchsine base (monohydrochloride) 是一种品红染料,经验证可用于石碳酸-品红的抗酸染色。
• 相关类别:
  信号通路 >> 其他 >> 其他
  染料试剂
  研究领域 >> 其他

MSDS

Name: Pararosaniline (Fuchsin Basic) Material Safety Data Sheet Synonym: Basic Violet 14, Hydrochloride; C.I. 42510; Rosaniline Chloride; Magenta CAS: 632-99-5 Section 1 - Chemical Product MSDS Name:Pararosaniline (Fuchsin Basic) Material Safety Data Sheet Synonym:Basic Violet 14, Hydrochloride; C.I. 42510; Rosaniline Chloride; Magenta Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 632-99-5 Pararosaniline (Fuchsin Basic) ca 100 211-189-6 Hazard Symbols: XN Risk Phrases: 33 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Danger of cumulative effects. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. If absorbed, causes symptoms similar to those of ingestion. Ingestion: May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. Exposure may cause anemia and other blood abnormalities. Inhalation: May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death. May cause effects similar to those described for ingestion. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. Prolonged exposure may cause anemia and methemoglobinemia, characterized by dizziness, drowsiness, headache, breath shortness, cyanosis (bluish skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. Chronic exposure can affect thyroid function. May cause pituitary gland abnormalities. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood. Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing Media: Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits CAS# 632-99-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: dark green Odor: Odorless pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 250 deg C dec Autoignition Temperature: Not applicable. Flash Point: 200 deg C ( 392.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: 200 deg C Solubility in water: 0.26% Specific Gravity/Density: Molecular Formula: C20H20ClN3 Molecular Weight: 337.84 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable. However, may decompose if heated. Conditions to Avoid: Incompatible materials, dust generation, excess heat. Incompatibilities with Other Materials: Aniline is incompatible with acetic anhydride, chlorosulfonic acid, hexachloromelamine, nitric acid , nitric acid + nitrogen tetroxide and sulfuric acid, nitrobenzene and glycerine, oleum, ozone, perchloric acid + formaldehyde, perchromates, performic acid, potassium peroxide, propiolactone(beta), silver perchlorate, sodium peroxide, sulfuric acid, trichloromelamine, oxidizing materials, acids, anilinium chloride, benzenediazonium-2-carboxylate, boron trichloride, 1-chloro-2,3-epoxypropane, dibenzoyl peroxide, nitromethane, nitrous acid, and tetranitromethane. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 632-99-5: CX9850000 LD50/LC50: Not available. Carcinogenicity: Pararosaniline (Fuchsin Basic) - IARC: Group 2B carcinogen Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 33 Danger of cumulative effects. Safety Phrases: S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 632-99-5: No information available. Canada CAS# 632-99-5 is listed on Canada's DSL List. CAS# 632-99-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 632-99-5 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水稍微有危害的，不要让未稀释或者大量产品接触地下水，水道或者污水系统。若无政府许可，勿将材料排入周围环境。 CHEMICAL IDENTIFICATION RTECS NUMBER : CX9850000 CHEMICAL NAME : Benzenamine, 4-((4-aminophenyl)(4-imino-2,5-cyclohexadien-1-yliden e)methyl)-2-methyl-, monohydrochloride CAS REGISTRY NUMBER : 632-99-5 LAST UPDATED : 199701 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C20-H19-N3.Cl-H MOLECULAR WEIGHT : 337.88 WISWESSER LINE NOTATION : L6Y DYJ AUYR DZ&R DZ C1& DUM &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 32 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,21,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,57,1974 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,57,1974 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,215,1993 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,238,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84118 No. of Facilities: 651 (estimated) No. of Industries: 11 No. of Occupations: 19 No. of Employees: 5303 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84405 No. of Facilities: 719 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 4356 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84118 No. of Facilities: 1281 (estimated) No. of Industries: 6 No. of Occupations: 15 No. of Employees: 12691 (estimated) No. of Female Employees: 8288 (estimated)

安全

• 危害码 (欧洲): Xn:Harmful
• 风险声明 (欧洲): R22;R40
• 安全声明 (欧洲): 7-16-36/37
• 危险品运输编码: UN 2924 3/PG 2
• WGK德国: 3
• RTECS号: CX9850000
• 危险类别: 3.0
• 海关编码: 3204130000

上下游产品

上游产品  0
下游产品  1
76-82-4

制备

1.制法 将苯胺、对甲苯胺和邻甲苯胺与硝基苯、氯化亚铁在一起熔融,进行氧化缩合,而后用硫酸溶解提取,再经中和、盐析、过滤及干燥即得成品。

2.把相等物质量的苯胺、对甲苯胺和邻甲苯胺混合，在含有五氧化二砷的砷酸中一起加热，反应完成后用水浸取，过滤，然后用盐酸酸化，即得碱性品红晶体。

海关

海关编码	2925290090
中文概述	2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%