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157528-81-9生产厂家

157528-81-9价格

157528-81-9

157528-81-9结构式
157528-81-9结构式
  • 常用中文名:二羟丙茶碱D甲醚
  • 常用英文名:Coronarin D methyl ether
  • CAS号:157528-81-9
  • 分子式:C21H32O3
  • 分子量:332.48
  • 相关类别: 天然产物 萜类
  • 发布时间:2017-03-14 22:59:33
  • 更新时间:2024-01-12 10:03:01
  • Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-魏B with an IC50 value of 7.3 渭M. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 渭M[1].

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中文名 二羟丙茶碱D甲醚
英文名 (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedec ahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
英文别名 (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-5-methoxy-, (3E)-
(3Z)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-5-methoxy-, (3Z)-
描述 甲氧基肝素D可以从冠毒黑豆中分离出来,是一种有效的NF抑制剂-魏IC50值为7.3的B渭M.Methoxycoronarin D也是COX-1的选择性抑制剂,IC50值为0.9渭M[1]。
相关类别
参考文献

[1]. Endringer D C, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium[J]. Revista Brasileira de Farmacognosia, 2014, 24: 408-412.

密度 1.0±0.1 g/cm3
沸点 447.8±45.0 °C at 760 mmHg
分子式 C21H32O3
分子量 332.48
闪点 191.7±23.3 °C
精确质量 332.235138
PSA 35.53000
LogP 5.65
外观性状 油状物体
蒸汽压 0.0±1.1 mmHg at 25°C
折射率 1.516
储存条件 2-8℃,干燥,密闭
危害码 (欧洲) Xi