13410-86-1

• 常用中文名：阿考烟肼
• 常用英文名：Aconiazide
• CAS号：13410-86-1
• 分子式：C₁₅H₁₃N₃O₄
• 分子量：299.28100
• 相关类别： 研究领域 感染
• 发布时间：2018-09-30 01:47:23
• 更新时间：2024-01-07 02:40:06
• Aconiazide(Isonicophen) 是一种口服活性的异烟肼衍生物,可用于结核病的研究。

名称

• 中文名: 阿考烟肼
• 英文名: 2-[2-[(E)-(pyridine-4-carbonylhydrazinylidene)methyl]phenoxy]acetic acid
• 英文别名: [2-(isonicotinoylhydrazono-methyl)-phenoxy]-acetic acid; Isonicophen; Aconiazid; Phenoxalid; ACONIAZIDE; [2-(Isonicotinoylhydrazono-methyl)-phenoxy]-essigsaeure

物化性质

• 密度: 1.3g/cm3
• 分子式: C₁₅H₁₃N₃O₄
• 分子量: 299.28100
• 精确质量: 299.09100
• PSA: 100.88000
• LogP: 1.69980
• 折射率: 1.61

生物活性

• 描述: Aconiazide(Isonicophen) 是一种口服活性的异烟肼衍生物,可用于结核病的研究。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. KENNETH L. DOOLEY, et al. Fourteen-Day , Repeat-Dose Toxicity Evaluation of Aconiazide _- Administered Orally to Male and Female Fischer 344 Rats. JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY Vdume 12, Number 4, 1993

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : US5638000 CHEMICAL NAME : 4-Pyridinecarboxylic acid, ((2-(carboxymethoxy)phenyl)methylene)hydrazide CAS REGISTRY NUMBER : 13410-86-1 BEILSTEIN REFERENCE NO. : 0300804 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C15-H13-N3-O4 MOLECULAR WEIGHT : 299.31 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7 gm/kg/14D-I TOXIC EFFECTS : Peripheral Nerve and Sensation - structural change in nerve or sheath Liver - fatty liver degeneration Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,329,1993 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 36400 mg/kg/26W-I TOXIC EFFECTS : Peripheral Nerve and Sensation - structural change in nerve or sheath Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 14,328,1995

安全

• 海关编码: 2933399090

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%