153408-27-6

• 常用中文名：盐酸氮卓斯汀
• 常用英文名：Azelastine Hydrochloride
• CAS号：153408-27-6
• 分子式：C₂₂H₂₅Cl₂N₃O
• 分子量：418.359
• 相关类别： 原料药 抗变态反应药 抗组胺药
• 发布时间：2018-06-09 21:09:08
• 更新时间：2024-01-10 07:26:05
• (S)-Azelastine hydrochloride is an antihistamine which has been shown to down-regulate H1R, M1R and M3R levels. This compound has also been shown to inhibit HNEpC proliferation.

名称

• 中文名: 盐酸氮卓斯汀
• 英文名: (S)-Azelastine Hydrochloride
• 中文别名: (S)-氮卓斯汀盐酸盐
• 英文别名: Azelastine hydrochloride; 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, hydrochloride (1:1); 4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloride; 4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)phthalazin-1(2H)-one hydrochloride; UNII:0L591QR10I; 1(2H)-phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride; 4-(4-Chlorobenzyl)-2-(1-methyl-4-azepanyl)-1(2H)-phthalazinone hydrochloride (1:1); 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride; azelastinum [INN_la]; 4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride (1:1); 4-(4-Chlorbenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-onhydrochlorid; 4-(4-chlorobenzyl)-2-(1-méthylazépan-4-yl)phtalazin-1(2H)-one chlorhydrate; 4-[(4-chlorophenyl)methyl]-2-[(4S)-1-methylazepan-4-yl]phthalazin-1-one,hydrochloride; Azelastine Impurity 2

物化性质

• 熔点: 225--229ºC
• 分子式: C₂₂H₂₅Cl₂N₃O
• 分子量: 418.359
• 精确质量: 417.137482
• PSA: 38.13000
• LogP: 5.03740
• 储存条件: -20°C Freezer