119478-55-6

• 常用中文名：甲磺酸达氟沙星
• 常用英文名：Danofloxacin Mesylate
• CAS号：119478-55-6
• 分子式：C₂₀H₂₄FN₃O₆S
• 分子量：453.484
• 相关类别： 原料药 人工合成抗感染类药 喹诺酮类药
• 发布时间：2018-06-14 22:14:07
• 更新时间：2024-01-02 14:46:20
• Danofloxacin(CP76136-27)甲磺酸盐是兽医用氟喹诺酮类抗菌素。

名称

• 中文名: 甲磺酸达氟沙星
• 英文名: Danofloxacin Mesylate
• 中文别名: 盐酸甲氧胺; 甲达沙星; 1-环丙基-6-氟-7-[(1S,4S)-5-甲基-2,5-二氮杂双环[2.2.1]庚烷-2-基]-1,4-二氢-4-氧代喹啉-3-羧酸甲磺酸盐; 甲磺酸丹诺沙星
• 英文别名: CP 76136-27; Danofioxacin Mesylate; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-, methanesulfonate (1:1); MFCD00673687; 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-3-quinolinecarboxylic Acid Monomethanesulfonate; 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate (1:1); 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate (1:1); Danofloxacin mesylate; Danofloxacin (mesylate)

物化性质

• 沸点: 569.3ºC at 760 mmHg
• 熔点: 337-339ºC
• 分子式: C₂₀H₂₄FN₃O₆S
• 分子量: 453.484
• 闪点: 298.1ºC
• 精确质量: 453.136993
• PSA: 128.53000
• LogP: 2.65410
• 外观性状: 结晶固体
• 蒸汽压: 8.41E-14mmHg at 25°C
• 储存条件: 0-6°C

生物活性

• 描述: Danofloxacin(CP76136-27)甲磺酸盐是兽医用氟喹诺酮类抗菌素。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  天然产物 >> 生物碱
  研究领域 >> 感染
• 参考文献:

  [1]. Giles, C.J., et al., Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. J Vet Pharmacol Ther, 1991. 14(4): p. 400-10.

  [2]. McGuirk, P.R., et al., Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine. J Med Chem, 1992. 35(4): p. 611-20.

安全

• 危害码 (欧洲): T+
• 海关编码: 2933990090

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%