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Lorglumide钠盐

更新时间:2024-01-07 21:19:23

Lorglumide钠盐结构式
Lorglumide钠盐结构式
品牌特惠专场
常用名 Lorglumide钠盐 英文名 Lorglumide sodium salt
CAS号 1021868-76-7 分子量 481.388
密度 N/A 沸点 N/A
分子式 C22H31Cl2N2NaO4 熔点 N/A
MSDS 中文版 美版 闪点 N/A

 Lorglumide钠盐用途


Lorglumide sodium salt (CR-1409 sodium salt) 是一种有效的胆囊收缩素(CCK)受体拮抗剂。

 Lorglumide钠盐名称

中文名 Lorglumide钠盐
英文名 Sodium 4-{[4-carboxylato-1-(dipentylamino)-1-oxo-2-butanyl]carbamoyl}-1,2-dichlorobenzene
英文别名 更多

 Lorglumide钠盐生物活性

描述 Lorglumide sodium salt (CR-1409 sodium salt) 是一种有效的胆囊收缩素(CCK)受体拮抗剂。
相关类别
靶点

CCK[1]

参考文献

[1]. Scarpignato C, et al. Effect of a new potent CCK antagonist, lorglumide, on caerulein- and bombesin-induced pancreatic secretion and growth in the rat. Br J Pharmacol. 1989 Mar;96(3):661-9.

 Lorglumide钠盐物理化学性质

分子式 C22H31Cl2N2NaO4
分子量 481.388
精确质量 480.155853
储存条件 2-8℃

 Lorglumide钠盐安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
RTECS号 SA3680700

 Lorglumide钠盐文献7

更多文献
Different downstream signalling of CCK1 receptors regulates distinct functions of CCK in pancreatic beta cells.

Br. J. Pharmacol. 172 , 5050-67, (2015)

Cholecystokinin (CCK) is secreted by intestinal I cells and regulates important metabolic functions. In pancreatic islets, CCK controls beta cell functions primarily through CCK1 receptors, but the si...

Involvement of different subtypes of cholecystokinin receptors in opioid antinociception in the mouse.

Peptides 16(7) , 1229-34, (1995)

Various doses of sulfated cholecystokinin octapeptide (CCK-8s) injected intracerebroventricularly (ICV) alone did not show any antinociceptive effect. CCK-8s (0.01-1 ng) pretreated ICV for 10 min dose...

Expression of the transcription factor Egr-1 in pancreatic acinar cells following stimulation of cholecystokinin or Gαq-coupled designer receptors.

Cell Physiol. Biochem. 33(5) , 1411-25, (2014)

BACKGOUND/AIMS: The injection of cerulein, an analogue of the pancreatic secretagogue cholecystokinin (CCK), induces acute pancreatitis in mice that is accompanied by the synthesis of the transcriptio...

 Lorglumide钠盐英文别名

Sodium 4-{[4-carboxylato-1-(dipentylamino)-1-oxobutan-2-yl]carbamoyl}-1,2-dichlorobenzene
Sodium 4-{[4-carboxylato-1-(dipentylamino)-1-oxo-2-butanyl]carbamoyl}-1,2-dichlorobenzene
MFCD00083183
品牌现货直购
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