Bavisant dihydrochloride hydrate

• 常用名: Bavisant dihydrochloride hydrate
• 英文名: Bavisant dihydrochloride hydrate
• CAS号: 1103522-80-0
• 分子量: 420.37400
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₃₁Cl₂N₃O₃
• 熔点: N/A
• 闪点: N/A

Bavisant dihydrochloride hydrate用途

Bavisant盐酸盐(JNJ-31001074)是口服活性人H3受体拮抗剂。

Bavisant dihydrochloride hydrate名称

• 中文名: Bavisant dihydrochloride hydrate
• 英文名: (4-cyclopropylpiperazin-1-yl)-[4-(morpholin-4-ylmethyl)phenyl]methanone,hydrate,dihydrochloride

Bavisant dihydrochloride hydrate生物活性

• 描述: Bavisant盐酸盐(JNJ-31001074)是口服活性人H3受体拮抗剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体
  信号通路 >> 免疫及炎症 >> 组胺受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Robert L. Hudkins, Rita Raddatz, Ming Tao, Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist. J. Med. Chem. 2011, 54

  [2]. Weisler RH, Pandina GJ, Daly EJ, Randomized clinical study of a histamine H3 receptor antagonist for the treatment of adults with attention-deficit hyperactivity disorder. CNS Drugs. 2012 May 1;26(5):421-34.

Bavisant dihydrochloride hydrate物理化学性质

• 分子式: C₁₉H₃₁Cl₂N₃O₃
• 分子量: 420.37400
• 精确质量: 419.17400
• PSA: 45.25000
• LogP: 2.79240
• 储存条件: 2-8℃

Bavisant dihydrochloride hydrate英文别名

• Methanone,(4-cyclopropyl-1-piperazinyl)(4-(4-morpholinylmethyl)phenyl)-,hydrochloride,hydrate (1:2:1)
• (4-Cyclopropylpiperazin-1-yl)(4-(morpholin-4-ylmethyl)phenyl)methanone dihydrochloride monohydrate
• BAVISANT DIHYDROCHLORIDE
• Bavisant dihydrochloride (USAN)
• UNII-C1H7H5X3RE
• Bavisant dihydrochloride hydrate
• Bavisant (dihydrochloride hydrate)