柚皮芸香苷

• 常用名: 柚皮芸香苷
• 英文名: Narirutin
• CAS号: 14259-46-2
• 分子量: 580.535
• 密度: 1.7±0.1 g/cm3
• 沸点: 924.3±65.0 °C at 760 mmHg
• 分子式: C₂₇H₃₂O₁₄
• 熔点: 152-190ºC
• 闪点: 307.3±27.8 °C

柚皮芸香苷用途

Narirutin 是从 Citrus unshiu 中分离的活性成分之一,具有抗氧化和抗炎活性。Narirutin 是一种具有抗结核效力的 shikimate 激酶抑制剂。

柚皮芸香苷名称

• 中文名: 芸香柚皮苷
• 英文名: narirutin
• 中文别名: 柚皮素-7-O-芸香糖苷 | 柚皮芸香苷

柚皮芸香苷生物活性

• 描述: Narirutin 是从 Citrus unshiu 中分离的活性成分之一,具有抗氧化和抗炎活性。Narirutin 是一种具有抗结核效力的 shikimate 激酶抑制剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Sahu PK, et al. Structure-based Discovery of Narirutin as a Shikimate Kinase Inhibitor with Anti-tubercular Potency.Curr Comput Aided Drug Des. 2019 Oct 25.

  [2]. Funaguchi N, et al. Narirutin inhibits airway inflammation in an allergic mouse model.Clin Exp Pharmacol Physiol. 2007 Aug;34(8):766-70.

柚皮芸香苷物理化学性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 924.3±65.0 °C at 760 mmHg
• 熔点: 152-190ºC
• 分子式: C₂₇H₃₂O₁₄
• 分子量: 580.535
• 闪点: 307.3±27.8 °C
• 精确质量: 580.179199
• PSA: 225.06000
• LogP: 2.07
• 外观性状: 灰白色粉末
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.708
• 储存条件: 室温

柚皮芸香苷安全信息

• 安全声明 (欧洲): 22-24/25
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 29389090

柚皮芸香苷英文别名

• (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl-6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
• (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside
• ISONARINGIN
• Isonaringenin
• Naringenin 7-O-rutinoside
• 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-
• Naringenin-7-rutinoside
• (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-one
• Narirutin
• (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
• (2S)-5-Hydroxy-2-(4-hydroxyphényl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromén-4-one
• Naringenin 7-rutinoside
• (S)-7-((6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• naringenin-7-O-rutinoside
• Apigenin-7-rutinosid
• (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-on