8-(3-Chlorostyryl)caffeine
8-(3-Chlorostyryl)caffeine结构式
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常用名 | 8-(3-Chlorostyryl)caffeine | 英文名 | 8-(3-Chlorostyryl)caffeine |
|---|---|---|---|---|
| CAS号 | 147700-11-6 | 分子量 | 330.76900 | |
| 密度 | 1.36g/cm3 | 沸点 | 559.4ºC at 760 mmHg | |
| 分子式 | C16H15ClN4O2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 292.1ºC |
8-(3-Chlorostyryl)caffeine用途(E) -8-(3-氯苯乙烯基)咖啡因是一种选择性腺苷A2A受体拮抗剂。(E) -8-(3-氯苯乙烯基)咖啡因通过独立于其对A2A受体的作用的途径抑制Ki值为70 nM的单胺氧化酶B(MAO-B)。(E) -8-(3-氯苯乙烯基)咖啡因有可能用于帕金森病研究[1]。 |
| 英文名 | 8-(3-chlorostyryl)caffeine |
|---|---|
| 英文别名 | 更多 |
| 描述 | (E) -8-(3-氯苯乙烯基)咖啡因是一种选择性腺苷A2A受体拮抗剂。(E) -8-(3-氯苯乙烯基)咖啡因通过独立于其对A2A受体的作用的途径抑制Ki值为70 nM的单胺氧化酶B(MAO-B)。(E) -8-(3-氯苯乙烯基)咖啡因有可能用于帕金森病研究[1]。 |
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| 相关类别 | |
| 靶点 |
A2AR MAO-B:70 nM (Ki) |
| 参考文献 |
| 密度 | 1.36g/cm3 |
|---|---|
| 沸点 | 559.4ºC at 760 mmHg |
| 分子式 | C16H15ClN4O2 |
| 分子量 | 330.76900 |
| 闪点 | 292.1ºC |
| 精确质量 | 330.08800 |
| PSA | 61.82000 |
| LogP | 1.79450 |
| 蒸汽压 | 1.52E-12mmHg at 25°C |
| 折射率 | 1.656 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
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| (E)-8-(3-chlorostyryl)-1,3,7-trimethylxanthine |
| (E)-1,3-Diethyl-8-(2-(3,4-dimethoxyphenyl)ethenyl)-3,7-dihydro-1H-purine-2,6-dione |
| (E)-8-[2-(3,4-dimethoxyphenyl)vinyl]-1,3-diethyl-3,7-dihydropurine-2,6-dione |
| 1H-Purine-2,6-dione,3,7-dihydro-1,3-diethyl-8-(2-(3,4-dimethoxyphenyl)ethenyl)-,(E) |
| 8-(3-Chlorostyryl)caffeine |
| (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-1H-purine-2,6(3H,7H)-dione |
| (E)-1,3,7-trimethyl-8-(3-chlorostyryl)xanthine |
| (E)-8-(3,4-Dimethoxystyryl)-1,3-diethylxanthine |
| 8-[(E)-2-(3-Chlorophenyl)vinyl]-1,3,7-trimethyl-3,7-dihydro-1H-pu rine-2,6-dione |
| 8-(3-chloro-(E)-styryl)caffeine |
| (E)-8-(3-chlorostyryl)-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione |
