奈非那韦

更新时间：2024-01-05 13:25:57

奈非那韦结构式	常用名	奈非那韦	英文名	Nelfinavir
	CAS号	159989-64-7	分子量	567.78
	密度	1.22g/cm3	沸点	786.8ºC at 760 mmHg
	分子式	C₃₂H₄₅N₃O₄S	熔点	N/A
	MSDS	N/A	闪点	429.7ºC

中文名	奈非那韦
英文名	nelfinavir
中文别名	娜芙维亚 \| 2-[(2R,3R)-2-羟基-3-[(3-羟基-2-甲基苯甲酰)氨基]-4-(苯基硫)丁基]-(3S,4aS,8aS)-N-叔丁基十氢异喹啉-3-甲酰胺
英文别名	更多

描述
相关类别	信号通路 >> 代谢酶/蛋白酶 >> HIV蛋白酶信号通路 >> 抗感染 >> HIV 研究领域 >> 感染
参考文献	[1]. Mondal D, et al. Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones. Ochsner J. 2013 Spring;13(1):76-90. [2]. Kaldor SW, et al. Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease. J Med Chem. 1997 Nov 21;40(24):3979-85.

描述

相关类别

信号通路 >> 代谢酶/蛋白酶 >> HIV蛋白酶

信号通路 >> 抗感染 >> HIV

研究领域 >> 感染

参考文献

[1]. Mondal D, et al. Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones. Ochsner J. 2013 Spring;13(1):76-90.

[2]. Kaldor SW, et al. Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease. J Med Chem. 1997 Nov 21;40(24):3979-85.

密度	1.22g/cm3
沸点	786.8ºC at 760 mmHg
分子式	C₃₂H₄₅N₃O₄S
分子量	567.78
闪点	429.7ºC
PSA	189.95000
LogP	6.05210
外观性状	白色至灰白色结晶粉末
蒸汽压	4.38E-26mmHg at 25°C
折射率	1.618
储存条件	2-8℃

奈非那韦上游产品 7
CAS号108-98-5 硫酚 CAS号188936-07-4 (3S,4aS,8aS)-2-... CAS号167678-46-8 3-乙酰氧基-2-甲基苯甲酰氯 CAS号128019-40-9 N-(TERT-BUTYL)D...
CAS号767341-27-5 3-(((2R,3S)-3,4... CAS号168899-58-9 3-乙酰氧基邻甲苯甲酸 CAS号767341-31-1 3-(((R)-1-((S)-...
奈非那韦下游产品 1
CAS号159989-65-8 甲磺酸奈非那韦

Methansulfonsäure--(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-{[(3-hydroxy-2-methylphenyl)carbonyl]amino}-4-(phenylsulfanyl)butyl]decahydroisochinolin-3-carboxamid(1:1)

Nelfinavir mesylate

Viracept (TN)

(3S,4aS,8aS)-N-tert-Butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfanyl)butyl]decahydroisoquinoline-3-carboxamide methanesulfonate (1:1)

Nelfinavir (INN)

Nelfinavir Monomethane Sulfonate

Viracept

acide méthanesulfonique - (3S,4aS,8aS)-N-(1,1-diméthyléthyl)-2-[(2R,3R)-2-hydroxy-3-{[(3-hydroxy-2-méthylphényl)carbonyl]amino}-4-(phénylsulfanyl)butyl]décahydroisoquinoléine-3-carboxamide (1:1)

AG1343

(3S,4AS,8AS)-2-[(2R,3R)-2-hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenylthiobutyl]decahydroisoquinoline-3-carboxylic acid t-butylamide

3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1) (salt)

(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]decahydroisoquinoline-3-carboxamide methanesulfonate (salt)

[3H]-Nelfinavir

UNII-HO3OGH5D7I

(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-{[(3-hydroxy-2-methylphenyl)carbonyl]amino}-4-(phenylsulfanyl)butyl]decahydroisoquinoline-3-carboxamide methanesulfonate (salt)

(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide

VRX496

[14C]-Nelfinavir

AZT/3TC/NLFR combination

(3S-(2(2S*,3S*),3-a,4ab,8ab))-N-(1,1-dimethylethyl)decahydro-2-(2-hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-4-(phenylthio)butyl)-3-isoquinolinecarboxamide monomethanesulfonate (salt)

(3S,4aS,8aS)-2-[(2R,3R)-2-Hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfanyl)butyl]-N-(2-methyl-2-propanyl)decahydro-3-isoquinolinecarboxamide methanesulfonate (1:1)

[3S-(3R*,4AR*,8AR*,2'S*,3'S*)]-2-[2'-Hydroxy-3'-phenylthiomethyl-4'-aza-5'-oxo-5'-(2''-methyl-3''-hydroxyphenyl)pentyl]decahydroisoquinoline-3-N-t-butylcarboxamide

1ohr