SB 205384结构式
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常用名 | SB 205384 | 英文名 | SB 205384 |
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| CAS号 | 160296-13-9 | 分子量 | 330.40 | |
| 密度 | 1.38g/cm3 | 沸点 | 565.3ºC at 760 mmHg | |
| 分子式 | C17H18N2O3S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 295.7ºC |
SB 205384用途SB-205384 是一种 GABAA 受体调节剂。SB-205384 对 GABAA 激活电流的主要影响是去除激动剂后反应衰减半衰期延长。 |
| 英文名 | but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylate |
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| 描述 | SB-205384 是一种 GABAA 受体调节剂。SB-205384 对 GABAA 激活电流的主要影响是去除激动剂后反应衰减半衰期延长。 |
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| 参考文献 |
| 密度 | 1.38g/cm3 |
|---|---|
| 沸点 | 565.3ºC at 760 mmHg |
| 分子式 | C17H18N2O3S |
| 分子量 | 330.40 |
| 闪点 | 295.7ºC |
| 精确质量 | 330.10400 |
| PSA | 113.68000 |
| LogP | 2.79780 |
| 蒸汽压 | 1.29E-13mmHg at 25°C |
| 折射率 | 1.691 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
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Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.
Mamm. Genome 21(5-6) , 247-57, (2010) The Tail Suspension Test (TST), which measures behavioral despair, is widely used as an animal model of human depressive disorders and antidepressant efficacy. In order to identify novel genes involve... |
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Developmental change in GABAA receptor desensitization kinetics and its role in synapse function in rat cortical neurons.
J. Physiol. 522 Pt 1 , 3-17, (2000) We examined the maturation of GABAA receptor synapses in cortical pyramidal neurons cultured from embryonic rats. The decay kinetics of GABAA receptor-mediated miniature postsynaptic currents (mPSCs) ... |
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SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity.
Br. J. Pharmacol. 123 , 1253-1259, (1998) 1. SB-205384, and its (+) enantiomer (+)-SB-205384 were tested for their modulatory effects on human GABA(A) receptor subunit combinations expressed in Xenopus oocytes by electrophysiological methods.... |
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