UK-414495

更新时间：2024-01-13 11:38:42

UK-414495结构式	常用名	UK-414495	英文名	UK-414495
	CAS号	337962-93-3	分子量	339.45
	密度	N/A	沸点	N/A
	分子式	C₁₆H₂₅N₃O₃S	熔点	N/A
	MSDS	N/A	闪点	N/A

UK-414495用途

(Rac)-UK-414495(实施例7)是一种有效的中性内肽酶(NEP)抑制剂。(Rac)-UK-414495引起女性性生殖器中cAMP的增强[1]。

英文名	2-[[1-[(5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclopentyl]methyl]pentanoic acid
英文别名	更多

描述	(Rac)-UK-414495(实施例7)是一种有效的中性内肽酶(NEP)抑制剂。(Rac)-UK-414495引起女性性生殖器中cAMP的增强[1]。
相关类别	研究领域 >> 代谢疾病信号通路 >> 代谢酶/蛋白酶 >> 脑啡肽酶
参考文献	[1]. Graham NM, et, al. NEP inhibitors for the treatment of female sexual dysfunction. EP1481667A1.

分子式	C₁₆H₂₅N₃O₃S
分子量	339.45
精确质量	339.16200
PSA	123.91000
LogP	4.13990

2-[1-([5-ethyl-[1,3,4]thiadiazol-2-yl]aminocarbonyl)cyclopentylmethyl]pentanoic acid tert-butyl ester结构式

2-[1-([5-ethyl-...

388630-83-9

~83%

UK-414495结构式

UK-414495

337962-93-3

文献：Pryde, David C.; Cook, Andrew S.; Burring, Denise J.; Jones, Lyn H.; Foll, Stephanie; Platts, Michelle Y.; Sanderson, Vivienne; Corless, Martin; Stobie, Alan; Middleton, Donald S.; Foster, Laura; Barker, Laura; Van Der Graaf, Piet; Stacey, Peter; Kohl, Christopher; Coggon, Sara; Beaumont, Kevin Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 142 - 159

(R)-1-[2-(tert-butoxycarbonyl)-4-pentenyl]-cyclopentane carboxylic acid结构式

(R)-1-[2-(tert-...

118783-85-0

~%

UK-414495结构式

UK-414495

337962-93-3

文献：Pryde, David C.; Maw, Graham N.; Planken, Simon; Platts, Michelle Y.; Sanderson, Vivienne; Corless, Martin; Stobie, Alan; Barber, Christopher G.; Russell, Rachel; Foster, Laura; Barker, Laura; Wayman, Christopher; Van Der Graaf, Piet; Stacey, Peter; Morren, Debbie; Kohl, Christopher; Beaumont, Kevin; Coggon, Sara; Tute, Michael Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4409 - 4424

环戊甲酸结构式

环戊甲酸

3400-45-1

~%

UK-414495结构式

UK-414495

337962-93-3

文献：Pryde, David C.; Maw, Graham N.; Planken, Simon; Platts, Michelle Y.; Sanderson, Vivienne; Corless, Martin; Stobie, Alan; Barber, Christopher G.; Russell, Rachel; Foster, Laura; Barker, Laura; Wayman, Christopher; Van Der Graaf, Piet; Stacey, Peter; Morren, Debbie; Kohl, Christopher; Beaumont, Kevin; Coggon, Sara; Tute, Michael Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4409 - 4424

1-[2-(tert-butoxycarbonyl)ethyl]-1-cyclopentanecarboxylic acid结构式

1-[2-(tert-buto...

118756-03-9

~%

UK-414495结构式

UK-414495

337962-93-3

文献：Pryde, David C.; Maw, Graham N.; Planken, Simon; Platts, Michelle Y.; Sanderson, Vivienne; Corless, Martin; Stobie, Alan; Barber, Christopher G.; Russell, Rachel; Foster, Laura; Barker, Laura; Wayman, Christopher; Van Der Graaf, Piet; Stacey, Peter; Morren, Debbie; Kohl, Christopher; Beaumont, Kevin; Coggon, Sara; Tute, Michael Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4409 - 4424

1-(2-tert-butoxycarbonyl-pentyl)cyclopentanecarboxylic acid结构式

1-(2-tert-butox...

337962-91-1

~%

UK-414495结构式

UK-414495

337962-93-3

文献：Pryde, David C.; Maw, Graham N.; Planken, Simon; Platts, Michelle Y.; Sanderson, Vivienne; Corless, Martin; Stobie, Alan; Barber, Christopher G.; Russell, Rachel; Foster, Laura; Barker, Laura; Wayman, Christopher; Van Der Graaf, Piet; Stacey, Peter; Morren, Debbie; Kohl, Christopher; Beaumont, Kevin; Coggon, Sara; Tute, Michael Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4409 - 4424

UK-414495上游产品 5
CAS号388630-83-9 2-[1-([5-ethyl-... CAS号118783-85-0 (R)-1-[2-(tert-... CAS号3400-45-1 环戊甲酸 CAS号118756-03-9 1-[2-(tert-buto...
CAS号337962-91-1 1-(2-tert-butox...
UK-414495下游产品 0

uk-414,495

上海源溪生物科技有限公司
上海市上海市浦东新区
产品名：UK-414495
纯度：98.9%
规格：1g
联系人：赖经理
联系电话：13564518121

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