3'-去磷酸辅酶 A

更新时间:2024-01-06 10:29:56

3'-去磷酸辅酶 A结构式
3'-去磷酸辅酶 A结构式
品牌特惠专场
常用名 3'-去磷酸辅酶 A 英文名 3'-O-dephosphono-coenzyme A
CAS号 3633-59-8 分子量 687.55400
密度 1.85±0.1 g/cm3(Predicted) 沸点 N/A
分子式 C21H35N7O13P2S 熔点 N/A
MSDS 美版 闪点 N/A

 3'-去磷酸辅酶 A用途

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去磷酸辅酶A是辅酶A(CoA)的直接前体。去磷酸辅酶A激酶(DPCK)催化去磷酸辅酶CoA的ATP依赖性磷酸化,这是辅酶A(CoA)生物合成的最后一步[1][2]。

 3'-去磷酸辅酶 A名称

中文名 3′-脱磷酸辅酶A
英文名 3'-dephospho-CoA
英文别名 更多

 3'-去磷酸辅酶 A生物活性

描述 去磷酸辅酶A是辅酶A(CoA)的直接前体。去磷酸辅酶A激酶(DPCK)催化去磷酸辅酶CoA的ATP依赖性磷酸化,这是辅酶A(CoA)生物合成的最后一步[1][2]。
相关类别
靶点

Human Endogenous Metabolite

参考文献

[1]. Swift RP, et al. Dephospho-CoA kinase, a nuclear-encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption. EMBO J. 2021 Aug 16;40(16):e107247.  

[2]. Shimosaka T, et al. Identification of Dephospho-Coenzyme A (Dephospho-CoA) Kinase in Thermococcus kodakarensis and Elucidation of the Entire CoA Biosynthesis Pathway in Archaea. mBio. 2019 Jul 23;10(4):e01146-19.  

 3'-去磷酸辅酶 A物理化学性质

密度 1.85±0.1 g/cm3(Predicted)
分子式 C21H35N7O13P2S
分子量 687.55400
精确质量 687.14900
PSA 358.45000
储存条件 -20 °C,密封,干燥

 3'-去磷酸辅酶 A安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport

 3'-去磷酸辅酶 A文献25

更多文献
Simultaneous high-performance liquid chromatography determination of coenzyme A, dephospho-coenzyme A, and acetyl-coenzyme A in normal and pantothenic acid-deficient rats.

Anal. Biochem. 430(2) , 151-5, (2012)

We describe here a simultaneous high-performance liquid chromatography method for practical and rapid determination of coenzyme A (CoA), dephospho-CoA, and acetyl-CoA in tissues. These coenzymes are b...

Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases.

Biochemistry 39(43) , 13233-40, (2000)

Malonate decarboxylase from Klebsiella pneumoniae contains an acyl carrier protein (MdcC) to which a 2'-(5' '-phosphoribosyl)-3'-dephospho-CoA prosthetic group is attached via phosphodiester linkage t...

Purification and characterization of phosphopantetheine adenylyltransferase from Escherichia coli.

J. Biol. Chem. 274(38) , 27105-11, (1999)

Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in coenzyme A (CoA) biosynthesis: the reversible adenylation of 4'-phosphopantetheine yielding 3'-dephospho-CoA and pyropho...

 3'-去磷酸辅酶 A英文别名

3′-Dephosphocoenzyme A
3'-DEPHOSPHOCOENZYME A
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