盐酸氮芥结构式
|
常用名 | 盐酸氮芥 | 英文名 | Chlormethine hydrochloride |
---|---|---|---|---|
CAS号 | 55-86-7 | 分子量 | 192.514 | |
密度 | 1.106g/cm3 | 沸点 | 110.3ºC at 760 mmHg | |
分子式 | C5H12Cl3N | 熔点 | 108-111 °C(lit.) | |
MSDS | 中文版 美版 | 闪点 | 20.5ºC | |
符号 |
GHS05, GHS06, GHS08 |
信号词 | Danger |
盐酸氮芥用途Chlormethine盐酸盐是一种发泡剂,对粘膜造成坏死性刺激性破坏。用在霍奇金病和淋巴瘤中抗肿瘤。 |
中文名 | 氮芥盐酸盐 |
---|---|
英文名 | mechlorethamine hydrochloride |
中文别名 | 恩比兴 | 二氯甲基二乙胺盐酸盐 | 盐酸氮芥 | 2-氯-N-(2-氯乙基)-N-甲基乙胺盐酸盐 | N-甲基-N-(2-氯乙基)-2-氯乙胺盐酸盐 |
英文别名 | 更多 |
描述 | Chlormethine盐酸盐是一种发泡剂,对粘膜造成坏死性刺激性破坏。用在霍奇金病和淋巴瘤中抗肿瘤。 |
---|---|
相关类别 | |
参考文献 |
密度 | 1.106g/cm3 |
---|---|
沸点 | 110.3ºC at 760 mmHg |
熔点 | 108-111 °C(lit.) |
分子式 | C5H12Cl3N |
分子量 | 192.514 |
闪点 | 20.5ºC |
精确质量 | 191.003525 |
PSA | 3.24000 |
LogP | 2.19780 |
外观性状 | 白色结晶粉末 |
折射率 | 1.4689 (24ºC) |
储存条件 | 库房通风低温干燥,与食品原料分开存放 |
稳定性 | Stable. Hygroscopic. |
计算化学 | 1.疏水参数计算参考值(XlogP):无 2.氢键供体数量:1 3.氢键受体数量:1 4.可旋转化学键数量:4 5.互变异构体数量:无 6.拓扑分子极性表面积3.2 7.重原子数量:9 8.表面电荷:0 9.复杂度:43.7 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:2 |
更多 | 1.熔点(℃):108-111。. |
符号 |
GHS05, GHS06, GHS08 |
---|---|
信号词 | Danger |
危害声明 | H300 + H310-H314-H340-H350-H360D |
警示性声明 | P201-P264-P280-P301 + P310-P302 + P350-P305 + P351 + P338 |
个人防护装备 | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
危害码 (欧洲) | T+:Verytoxic; |
风险声明 (欧洲) | R45;R46;R28;R34;R42/43 |
安全声明 (欧洲) | S53-S36/37/39-S45 |
危险品运输编码 | UN 2811 6.1/PG 2 |
WGK德国 | 3 |
RTECS号 | IA2100000 |
包装等级 | II |
危险类别 | 6.1(a) |
海关编码 | 2921199090 |
盐酸氮芥上游产品 5 | |
---|---|
盐酸氮芥下游产品 10 | |
海关编码 | 2921199090 |
---|---|
中文概述 | 2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0% |
申报要素 | 品名, 成分含量, 用途 |
Summary | 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.
Hum. Mol. Genet. 24(3) , 698-713, (2015) Congenital brain and craniofacial defects often occur together as a consequence of their developmental dependency on common progenitor tissue interactions and signaling pathways during embryogenesis. ... |
|
Lethality of PAK3 and SGK2 shRNAs to human papillomavirus positive cervical cancer cells is independent of PAK3 and SGK2 knockdown.
PLoS ONE 10(1) , e0117357, (2015) The p21-activated kinase 3 (PAK3) and the serum and glucocorticoid-induced kinase 2 (SGK2) have been previously proposed as essential kinases for human papillomavirus positive (HPV+) cervical cancer c... |
|
Developing Adnectins that target SRC co-activator binding to PXR: a structural approach toward understanding promiscuity of PXR.
J. Mol. Biol. 427(4) , 924-42, (2015) The human pregnane X receptor (PXR) is a promiscuous nuclear receptor that functions as a sensor to a wide variety of xenobiotics and regulates expression of several drug metabolizing enzymes and tran... |
Ethanamine, 2-chloro-N- (2-chloroethyl)-N-methyl-, hydrochloride |
n-lost |
pliva |
Mustargen hydrochloride |
β,β'-Dichlorodiethyl-N-methylamine hydrochloride |
2-Chlor-N-(2-chlorethyl)-N-methylethanaminhydrochlorid |
Methyldi(β-chloroethyl)amine hydrochloride |
Mechlorethamine HCl |
Cloramin |
2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride |
Nitrogen mustard HCl |
MFCD00012517 |
bis(2-chlorolthyl)amine hydrochloride |
zagreb |
EINECS 200-246-0 |
Methylbis(β-chloroethyl)amine hydrochloride |
c6866 |
b,b'-Dichlorodiethyl-N-methylamine Hydrochloride |
chloramin |
N-Methylbis(β-chlorethyl)amine hydrochloride |
dimitan |
Nitrogranulogen |
erasol |
antimit |
dichloren |
Embichen |
Bis(2-chloroethyl)methylamine hydrochloride |
Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, hydrochloride (1:1) |
Mechlorethamine hydrochloride |
SK 101 |
2-chloro-N-(2-chloroéthyl)-N-méthyléthanamine chlorhydrate |
2-Chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride (1:1) |
MBA hydrochloride |
Chlormethine (hydrochloride) |