盐酸环喷托酯

更新时间：2024-01-08 12:41:05

盐酸环喷托酯结构式	常用名	盐酸环喷托酯	英文名	Cyclopentolate Hydrochloride
	CAS号	5870-29-1	分子量	327.84600
	密度	N/A	沸点	409.7ºC at 760mmHg
	分子式	C₁₇H₂₆ClNO₃	熔点	137-141°
	MSDS	N/A	闪点	201.5ºC

盐酸环喷托酯用途

Cyclopentolate (DL-Cyclopentolate) hydrochloride 是眼科常用的抗毒蕈碱药物。Cyclopentolate hydrochloride 是一种阿托品样毒蕈碱受体 (muscarinic receptor) 拮抗剂,对睫状肌毒蕈碱受体的 pKB 值为 7.8。

中文名	盐酸环喷托酯
英文名	Cyclopentolate Hydrochloride
中文别名	环戊通
英文别名	更多

描述	Cyclopentolate (DL-Cyclopentolate) hydrochloride 是眼科常用的抗毒蕈碱药物。Cyclopentolate hydrochloride 是一种阿托品样毒蕈碱受体 (muscarinic receptor) 拮抗剂,对睫状肌毒蕈碱受体的 pKB 值为 7.8。
相关类别	信号通路 >> 神经信号通路 >> mAChR 信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR 研究领域 >> 神经疾病
体内研究	环戊酯(20 mg/kg)预处理大鼠的存活率为90%[3]。动物模型：80只Sprague-Dawley大鼠(急性、致死性有机磷农药(OP)中毒模型)[3]剂量：20 mg/kg(眼用环戊酸钠)给药：i.p.结果：经眼用环戊酸钠(20 mg/kg)预处理的大鼠存活率为90%。
参考文献	[1]. Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond). 2016;30(7):925‐928. [2]. Ishikawa H, DeSantis L, Patil PN. Selectivity of muscarinic agonists including (+/-)-aceclidine and antimuscarinics on the human intraocular muscles. J Ocul Pharmacol Ther. 1998;14(4):363‐373. [3]. Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond). 2016;30(7):925‐928.

沸点	409.7ºC at 760mmHg
熔点	137-141°
分子式	C₁₇H₂₆ClNO₃
分子量	327.84600
闪点	201.5ºC
精确质量	327.16000
PSA	49.77000
LogP	2.98210
储存条件	−20°C
水溶解性	Very soluble in water, freely soluble in ethanol (96 per cent). It shows polymorphism (5.9).

盐酸环喷托酯毒性英文版

危害码 (欧洲)	Xi
危险品运输编码	NONH for all modes of transport
WGK德国	2
RTECS号	GY2450000
海关编码	2922509090

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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