2-(Dimethylamino)ethanol

2-(Dimethylamino)ethanol Structure
2-(Dimethylamino)ethanol structure
Common Name 2-(Dimethylamino)ethanol
CAS Number 108-01-0 Molecular Weight 89.136
Density 0.9±0.1 g/cm3 Boiling Point 135.0±0.0 °C at 760 mmHg
Molecular Formula C4H11NO Melting Point −70 °C(lit.)
MSDS Chinese USA Flash Point 40.6±0.0 °C
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger

Enzymatic properties and substrate specificity of a bacterial phosphatidylcholine synthase.

FEBS J. 281(15) , 3523-41, (2014)

Phosphatidylcholine (PC) is a rare membrane lipid in bacteria, but is crucial for virulence of the plant pathogen Agrobacterium tumefaciens and various other pathogens. Agrobacterium tumefaciens uses two independent PC biosynthesis pathways. One is dependent ...

Functionalization of 6-nitrobenzo[1,3]dioxole with carbonyl compounds via TDAE methodology.

Molecules 10(3) , 545-51, (2005)

We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and al...

Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies.

Psychopharmacology 207(2) , 201-12, (2009)

Dimethylaminoethanol pyroglutamate (DMAE p-Glu) is a compound resulting from the reaction between dimethylaminoethanol (an indirect precursor of acetylcholine) and pyroglutamic acid (a cyclic derivative of glutamic acid having procholinergic properties and pr...

Structural characterization and stability of dimethylaminoethanol and dimethylaminoethanol bitartrate for possible use in cosmetic firming.

J. Cosmet. Sci. 61(4) , 269-78, (2010)

2-Dimethylaminoethanol (DMAE) (also known as deanol) has been used as an ingredient in skin care, and in cognitive function- and mood-enhancing products. It is marketed as a free base or salt, and in theory, the two forms should be equally effective and able ...

Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness.

Phytomedicine 14(11) , 711-5, (2007)

Tricutan is a combination product of herbal extracts traditionally used for treatment of skin conditions, together with dimethylaminoethanol. The effectiveness of Tricutan in improving skin firmness and elasticity in photoaged facial skin was examined in a ra...

Quantitative determination of dimethylaminoethanol in cosmetic formulations by nuclear magnetic resonance spectroscopy.

J. AOAC Int. 91(6) , 1303-8, (2008)

A nuclear magnetic resonance (NMR) spectroscopic method was validated for the quantitative determination of dimethylaminoethanol (DMAE) in cosmetic formulations. The linearity in the range from 0.5000 to 1.5000 g (DMAE salt/mass maleic acid) presents a correl...

Recovery of choline oxidase activity by in vitro recombination of individual segments.

Appl. Microbiol. Biotechnol. 81(2) , 275-82, (2008)

Initial attempts to express a choline oxidase from Arthrobacter pascens (APChO-syn) in Escherichia coli starting from a synthetic gene only led to inactive protein. However, activity was regained by the systematic exchange of individual segments of the gene w...

In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation.

Pharmazie 64(12) , 818-22, (2009)

Dimethylaminoethanol (DMAE) has been used in anti-aging formulations but few scientifically based data address its efficacy. The aim of this study was to evaluate the effects of DMAE-based formulations on hairless mice and human skin. Formulations containing ...

Dimethylaminoethanol affects the viability of human cultured fibroblasts.

Aesthetic Plast. Surg. 31(6) , 711-8, (2007)

In clinical practice, dimethylaminoethanol (DMAE) has been used in the fight against wrinkles and flaccidity in the cervicofacial region. The firming action of DMAE is explained by the fact that its molecule, considered to be a precursor of acetylcholine, alt...

Improved quality control of [18F]fluoromethylcholine.

Nucl. Med. Biol. 38(8) , 1143-8, (2011)

With respect to the broad application of [(18)F-methyl]fluorocholine (FCH), there is a need for a safe, but also efficient and convenient way for routine quality control of FCH. Therefore, a GC- method should be developed and validated which allows the simult...