4,4'-PCB
4,4'-PCB structure
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Common Name | 4,4'-PCB | ||
|---|---|---|---|---|
| CAS Number | 2050-68-2 | Molecular Weight | 223.098 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 318.0±17.0 °C at 760 mmHg | |
| Molecular Formula | C12H8Cl2 | Melting Point | 288℃ | |
| MSDS | N/A | Flash Point | 145.2±14.5 °C | |
| Symbol |
GHS02, GHS07, GHS08, GHS09 |
Signal Word | Danger | |
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Microbial dehalogenation of 4,4'-dichlorobiphenyl under anaerobic conditions.
Sci. Total Environ. 101(3) , 263-8, (1991) Anaerobic cultures containing 4,4'-dichlorobiphenyl (4,4'CB) were inoculated with various environmental samples. The degradation of the substrate was followed by gas chromatographic analysis. Three of the cultures tested showed an ability to dehalogenate the ... |
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Possible molecular targets of halogenated aromatic hydrocarbons in neuronal cells.
Biochem. Biophys. Res. Commun. 280(5) , 1372-7, (2001) Halogenated aromatic hydrocarbon including polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental toxicants. Although health effects associated with exposure to these chemicals, including motor dysfunction and impairment in memory a... |
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The effect of chlorine substitution on the disposition of polychlorinated biphenyls following dermal administration.
Toxicol. Appl. Pharmacol. 216(1) , 157-67, (2006) The fate of selected polychlorobiphenyls (PCBs) was investigated following single dermal administration (0.4 mg/kg) to determine the effects of chlorine content and position on the disposition of PCBs following dermal absorption. Single dermal doses of (14)C-... |
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Direct chloride measurement of [4-36Cl]chlorobiphenyl and [4,4'-36Cl]dichlorobiphenyl dechlorination in the rat.
J. Pharm. Sci. 73(8) , 1171-2, (1984) A reverse-phase HPLC system was used for the determination of inorganic chloride liberated in vivo from two biphenyl compounds in the rat. Oral administration of [4-36Cl]chlorobiphenyl resulted in a total yield of 27.6% of the original dose excreted over 10 d... |
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Accumulation and excretion of isopropylchlorobiphenyls in mouse and fish.
Bull. Environ. Contam. Toxicol. 26(1) , 46-53, (1981)
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Uptake of 4-chlorobiphenyl and 4,4'-dichlorobiphenyl in six species of plant tissue cultures.
Bull. Environ. Contam. Toxicol. 28(6) , 728-32, (1982)
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Induction of cytochrome P-450b,e-type isozymes by polychlorinated biphenyls in rat liver. Molecular cloning of induced mRNAs.
Eur. J. Biochem. 151(1) , 67-73, (1985) We have studied the induction of cytochrome P-450b,e-type antigen and mRNA by phenobarbital, 4,4'-dichlorobiphenyl and 2,4,5,2',4',5'-hexachlorobiphenyl in male Wistar rat liver. Chronic treatment of rats with 4,4'-dichlorobiphenyl leads to a relatively slow,... |
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Induction of drug metabolism enzymes by dihalogenated biphenyls.
J. Biochem. Toxicol. 5(1) , 57-63, (1990) The effects of pretreatment with symmetrically dihalogenated biphenyls (DXBs, X-F, Cl(C), Br(B) and I) on rat liver drug metabolism enzymes were investigated. 4,4'-DFB, -DCB, and -DBB as well as 2,2'-DFB appeared to be inducers of microsomal cytochrome P-450-... |
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Dissolved organic carbon--contaminant interaction descriptors found by 3D force field calculations.
SAR QSAR Environ. Res. 13(2) , 271-80, (2002) Enthalpies of transfer at 300 K of various partitioning processes were calculated in order to study the suitability of 3D force fields for the calculation of partitioning constants. A 3D fulvic acid (FA) model of dissolved organic carbon (DOC) was built in a ... |
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Comparative toxicokinetics of 2,2'- and 4,4'-dichlorobiphenyls in the pond snail Lymnaea stagnalis (L.).
Arch. Environ. Contam. Toxicol. 19(4) , 565-71, (1990) Pond snails (Lymnaea stagnalis (L.)) were treated with 2,2'-dichlorobiphenyl (DCB) or 4,4'-DCB, to examine the toxicokinetic profile of these compounds. Snails were treated orally with 210 micrograms 4,4'-DCB (impregnated on food) for 14 hr, or snails were in... |