agaric acid
agaric acid structure
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Common Name | agaric acid | ||
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| CAS Number | 666-99-9 | Molecular Weight | 416.54900 | |
| Density | 1.115g/cm3 | Boiling Point | 509.3ºC at 760 mmHg | |
| Molecular Formula | C22H40O7 | Melting Point | 142° (dec) | |
| MSDS | Chinese USA | Flash Point | 275.9ºC | |
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Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity.
Mitochondrion 5 , 272-281, (2005) The effect of agaric acid as inducer of mitochondrial permeability transition was studied. It was found that: (i) agaric acid (AA) promoted efflux of accumulated Ca2+, collapse of transmembrane potential, and mitochondrial swelling; (ii) these effects depend ... |
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The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane.
J. Bioenerg. Biomembr. 31 , 447-455, (1999) Nonesterified long-chain fatty acids have long been known as uncouplers of oxidative phosphorylation. They are efficient protonophores in the inner mitochondrial membrane but not so in artificial phospholipid membranes. In the un-ionized form, they undergo a ... |
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The effect of N-ethylmaleimide on permeability transition as induced by carboxyatractyloside, agaric acid, and oleate.
Cell Biochem. Biophys. 51 , 81-87, (2008) In this work, we studied the effect of N-ethylmaleimide on permeability transition. The findings indicate that the amine inhibited the effects of carboxyatractyloside and agaric acid. It is known that these reagents interact with the adenine nucleotide carrie... |
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Metabolic interconnection between the human malarial parasite Plasmodium falciparum and its host erythrocyte. Regulation of ATP levels by means of an adenylate translocator and adenylate kinase.
J. Biol. Chem. 264(6) , 3194-9, (1989) The metabolic inter-relationships between malarial parasites and their host erythrocytes are poorly understood. They have been investigated hitherto mostly by observing parasite behavior in erythrocyte variants, in metabolically altered erythrocytes, or in ce... |
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Agaric acid.
Meth. Enzymol. 72 , 497-506, (1981)
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[Cellular uptake and cytotoxicity of modified chitosans as gene carriers].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 28(4) , 486-91, (2006) To evaluate the effects of arginine modified chitosan or hexadecylated modified chitosan as gene carriers on the cellular uptake by vascular smooth muscle cells and its in vitro cytotoxicity. METHODS Plasmid DNA was labeled with alpha-32P-dATP and complexed w... |
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Development and characterization of an immobilized enzyme reactor based on glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies.
J. Chromatogr. A. 987(1-2) , 331-40, (2003) The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been extensively studied as a target for new drugs to be used in the treatment of various parasitic diseases. The standard approach to the determination of GAPDH activity utilizes solu... |
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Glucocorticoid induction of fatty-acid synthase mediates the stimulatory effect of the hormone on choline-phosphate cytidylyltransferase activity in fetal rat lung.
Biochim. Biophys. Acta 1044(1) , 70-6, (1990) Fetal lung fatty-acid synthase and choline-phosphate cytidylyltransferase activities are increased by glucocorticoids. There is evidence that the hormone increases synthesis of fatty-acid synthase but only increases the catalytic activity of the cytidylyltran... |
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Metabolic pathways involved in lipogenesis from lactate and acetate in bovine adipose tissue: effects of metabolic inhibitors.
Arch. Biochem. Biophys. 211(1) , 202-10, (1981)
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Inhibition by potential metabolic inhibitors of in vitro adipose tissue lipogenesis.
Comp. Biochem. Physiol.,. B. 81(3) , 667-70, (1985) To study the pathway of lactate utilization as a carbon source for fatty acid synthesis, the effect of (-)-hydroxycitrate, agaric acid, sodium oxamate, 2-n-butyl malonate and alpha-cyano-4-hydroxycinnamate on the rate of in vitro conversion of lactate, acetat... |