indolecarboxaldehyde

indolecarboxaldehyde Structure
indolecarboxaldehyde structure
Common Name indolecarboxaldehyde
CAS Number 19005-93-7 Molecular Weight 145.16
Density 1.3±0.1 g/cm3 Boiling Point 339.1±15.0 °C at 760 mmHg
Molecular Formula C9H7NO Melting Point 138-142ºC
MSDS Chinese USA Flash Point 166.8±27.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alkyl a...

Carbopalladation of nitriles: synthesis of 2,3-diarylindenones and polycyclic aromatic ketones by the Pd-catalyzed annulation of alkynes and bicyclic alkenes by 2-iodoarenenitriles.

J. Org. Chem. 26 , 9276, (2002)

2-iodobenzonitrile, its derivatives, and various heterocyclic analogues undergo palladium(0)-catalyzed annulation onto diarylacetylenes or bicyclic alkenes to afford 2,3-diarylindenones and polycyclic aromatic ketones in very good to excellent yields. This re...

Chem. Pharm. Bull. 39 , 2170, (1991)