Fucoidan
Fucoidan structure
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Common Name | Fucoidan | ||
|---|---|---|---|---|
| CAS Number | 9072-19-9 | Molecular Weight | 242.24700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H14O7S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Antiproliferative activity of fucan nanogel.
Mar. Drugs 10(9) , 2002-22, (2012) Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated L-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses. To that end, a non toxic fucan extracted from Spatoglossum schröederi was c... |
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Targeting P-selectin by gallium-68-labeled fucoidan positron emission tomography for noninvasive characterization of vulnerable plaques: correlation with in vivo 17.6T MRI.
Arterioscler. Thromb. Vasc. Biol. 34(8) , 1661-7, (2014) Nuclear imaging of active plaques still remains challenging. Advanced atherosclerotic plaques have a strong expression of P-selectin by the endothelium overlying active atherosclerotic plaques, but not on the endothelium overlying inactive fibrous plaques. We... |
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Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects.
Br. J. Nutr. 110(5) , 880-90, (2013) Laminaria japonica is traditionally eaten in Japan as a beneficial food for thrombosis. The alga contains two specific ingredients, a xanthophyll fucoxanthin (FX) and a polysaccharide, F-fucoidan (FD). The aim of the present study was to investigate whether F... |
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Fucoidan directly regulates the chemotaxis of canine peripheral blood polymorphonuclear cells by activating F-actin polymerization.
Vet. Immunol. Immunopathol. 151(1-2) , 124-31, (2013) Fucoidan was recently shown to enhance innate immune functions. The objective of this study was to examine the direct stimulatory effect of fucoidan on the chemotactic activity of canine peripheral blood polymorphonuclear cells (PMNs). The chemotactic activit... |
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Effect of fucoidan extracted from mozuku on experimental cartilaginous tissue injury.
Mar. Drugs 10(11) , 2560-70, (2012) We investigated the effect of fucoidan, a sulfated polysaccharide, on acceleration of healing of experimental cartilage injury in a rabbit model. An injured cartilage model was surgically created by introduction of three holes, one in the articular cartilage ... |
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RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formation.
J. Biol. Chem. 288(47) , 34230-8, (2013) We investigated the mechanism of activation and functional role of a hitherto uncharacterized signaling molecule, RhoG, in platelets. We demonstrate for the first time the expression and activation of RhoG in platelets. Platelet aggregation, integrin αIIbβ3 a... |
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Fucoidan prevents multiple myeloma cell escape from chemotherapy-induced drug cytotoxicity.
Fitoterapia 84 , 257-63, (2013) Minimal residual disease (MRD) occurrence with some chemotherapy drugs that promote tumor cell escape is also a key factor in blood malignancy relapse. We observed that cytarabine promotes multiple myeloma (MM) cell escape and that the number of cells in the ... |
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Preparation and characterization of fucoidan-chitosan nanospheres by the sonification method.
J. Nanosci. Nanotechnol. 14(5) , 3844-9, (2014) Fucoidan was chosen a substitute for alginate in chitosan-based polyelectrolytes or polyiones because it is negatively charged and possesses pharmacological properties. The fucoidan-chitosan nanospheres were prepared by the sonification method, and different ... |
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Novel hydrocolloid-sheet as wound dressing to stimulate healing-impaired wound healing in diabetic db/db mice.
Biomed Mater Eng 22(5) , 301-10, (2012) To create a moist environment for wound healing, a hydrocolloid-sheet composed of alginate, chitin/chitosan and fucoidan (ACF-HS) has been developed as a functional wound dressing. ACF-HS gradually adsorbed medium without any maceration and the medium adsorpt... |
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In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus.
Virol. J. 9 , 307, (2012) Newcastle Disease Virus (NDV) causes a serious infectious disease in birds that results in severe losses in the worldwide poultry industry. Despite vaccination, NDV outbreaks have increased the necessity of alternative prevention and control measures. Several... |