Dichloromethane
Dichloromethane structure
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Common Name | Dichloromethane | ||
|---|---|---|---|---|
| CAS Number | 75-09-2 | Molecular Weight | 84.933 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 39.6±0.0 °C at 760 mmHg | |
| Molecular Formula | CH2Cl2 | Melting Point | -97 °C | |
| MSDS | Chinese USA | Flash Point | -14.1±22.4 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.
J. Chromatogr. A. 1361 , 265-76, (2014) This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse urine. Samples were obtained from a murine model that mimics... |
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Synergistic activity of tenofovir and nevirapine combinations released from polycaprolactone matrices for potential enhanced prevention of HIV infection through the vaginal route.
Eur. J. Pharm. Biopharm. 88(2) , 406-14, (2014) Polycaprolactone (PCL) matrices were simultaneously loaded with the antiviral agents, tenofovir (TFV) and nevirapine (NVP), in combination to provide synergistic activity in the prevention of HIV transmission through the vaginal route. TFV and NVP were incorp... |
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Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response.
Eur. J. Pharm. Biopharm. 89 , 30-9, (2015) Novel PEGylated PLA nanocapsules (PEG-AcPLA nanocapsules), loading high percentage of water soluble drugs have been formulated by using multiple emulsion technique without using conventional stabilizers. In particular, sodium deoxycholate hydrate has been use... |
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Studying the chemistry of cationized triacylglycerols using electrospray ionization mass spectrometry and density functional theory computations.
J. Am. Soc. Mass Spectrom. 25(8) , 1421-40, (2014) Analysis of triacylglycerols (TAGs), found as complex mixtures in living organisms, is typically accomplished using liquid chromatography, often coupled to mass spectrometry. TAGs, weak bases not protonated using electrospray ionization, are usually ionized b... |
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Rapid detection of sugar alcohol precursors and corresponding nitrate ester explosives using direct analysis in real time mass spectrometry.
Analyst 140(8) , 2785-96, (2015) This work highlights the rapid detection of nitrate ester explosives and their sugar alcohol precursors by direct analysis in real time mass spectrometry (DART-MS) using an off-axis geometry. Demonstration of the effect of various parameters, such as ion pola... |
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Development and validation of a stability-indicating LC-UV method for the determination of pantethine and its degradation product based on a forced degradation study.
J. Pharm. Biomed. Anal. 97 , 141-50, (2014) Pantethine (d-bis-(N-pantothenyl-β-aminoethyl)-disulfide, PAN), the stable disulfide form of pantetheine, has beneficial effects in vascular diseases being able to decrease the hyperlipidaemia, moderate the platelet function and prevent the lipid peroxidation... |
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A new magnetic nanocapsule containing 5-fluorouracil: in vivo drug release, anti-tumor, and pro-apoptotic effects on CT26 cells allograft model.
J. Biomater. Appl. 29(4) , 548-56, (2014) The purpose of this study was to create an optimized method for preparation of 5-fluorouracil-loaded magnetic poly lactic-co-glycolic acid nanocapsules and to investigate its potential as multifunctional carriers to deliver therapeutic agents for tumor-target... |
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Biocompatible, biodegradable and porous liquid crystal elastomer scaffolds for spatial cell cultures.
Macromol. Biosci. 15(2) , 200-14, (2015) Here we report on the modular synthesis and characterization of biodegradable, controlled porous, liquid crystal elastomers (LCE) and their use as three-dimensional cell culture scaffolds. The elastomers were prepared by cross-linking of star block-co-polymer... |
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Evaluation of polycaprolactone matrices for sustained vaginal delivery of nevirapine in the prevention of heterosexual HIV transmission.
J. Pharm. Sci. 103(7) , 2107-15, (2014) Nevirapine (NVP) was loaded in polycaprolactone (PCL) matrices to produce vaginal inserts with the aim of preventing HIV transmission. NVP dispersions in PCL were prepared, at 10% (w/w) theoretical loading, measured with respect to the PCL content of the matr... |
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Lung deposition and cellular uptake behavior of pathogen-mimicking nanovaccines in the first 48 hours.
Adv. Healthc. Mater. 3(7) , 1071-7, (2014) Pulmonary immunization poses the unique challenge of balancing vaccine efficacy with minimizing inflammation in the respiratory tract. While previous studies have shown that mice immunized intranasally with F1-V-loaded polyanhydride nanoparticles are protecte... |