Pulegone

Pulegone Structure
Pulegone structure
Common Name Pulegone
CAS Number 89-82-7 Molecular Weight 152.233
Density 0.9±0.1 g/cm3 Boiling Point 224.0±0.0 °C at 760 mmHg
Molecular Formula C10H16O Melting Point N/A
MSDS Chinese USA Flash Point 82.2±0.0 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

R(+)-pulegone impairs Ca²+ homeostasis and causes negative inotropism in mammalian myocardium.

Eur. J. Pharmacol. 672(1-3) , 135-42, (2011)

The present study aimed to investigate the inotropic effects of R(+)-pulegone, a monoterpene found in plant species belonging to the genus Mentha, on the mammalian heart. In electrically stimulated guinea pig atria, R(+)-pulegone reduced the contractile force...

Synthesis of (R)-(+)-4-methylcyclohex-2-ene-1-one.

J. Org. Chem. 77(20) , 9422-5, (2012)

A three-step synthesis of (R)-(+)-4-methylcyclohex-2-ene-1-one (1) from (R)-(+)-pulegone (3), proceeding in 44% overall yield, is described. The sequence comprises vinyl triflate formation, site-selective ozonolysis, and reduction. The route requires only one...

Intraspecific variability of the essential oil of Calamintha nepeta subsp. nepeta from Southern Italy (Apulia).

Nat. Prod. Res. 27(4-5) , 331-9, (2013)

The essential oil of 46 spontaneous plants of Calamintha nepeta (L.) Savi subsp. nepeta growing wild in Sud, Italy (Salento, Apulia), were investigated by GC/MS. Fifty-seven components were identified in the oil representing over the 98% of the total oil comp...

Pharmacological activity of (R)-(+)-pulegone, a chemical constituent of essential oils.

Z. Naturforsch., C, J. Biosci. 66(7-8) , 353-9, (2011)

(R)-(+)-Pulegone is a monoterpene found in essential oils from plants of the Labiatae family. This compound is a major constituent of Agastache formosanum oil. In this study, the effect of (R)-(+)-pulegone on the central nervous system was evaluated. (R)-(+)-...

Chemical diversity among the essential oils of wild populations of Stachys lavandulifolia VAHL (Lamiaceae) from Iran.

Chem. Biodivers. 10(2) , 262-73, (2013)

The variation of the essential-oil composition among ten wild populations of Stachys lavandulifolia VAHL (Lamiaceae), collected from different geographical regions of Iran, was assessed by GC-FID and GC/MS analyses, and their intraspecific chemical variabilit...

Relaxant effects of the essential oil of Mentha pulegium L. in rat isolated trachea and urinary bladder.

J. Pharm. Pharmacol. 64(12) , 1777-84, (2012)

We evaluated the relaxant activity of the essential oil of Mentha pulegium L. (EOMP) and pulegone in rat isolated tracheal and bladder smooth muscles.ISOMETRIC contractions of isolated tracheal and bladder strips from male Wistar rats were induced by KCl (K60...

Chemical diversity of Ziziphora clinopodioides: composition of the essential oil of Z. clinopodioides from Tajikistan.

Nat. Prod. Commun. 6(5) , 695-8, (2011)

The chemical composition of the essential oils of Ziziphora clinopodioides Lam. from the aerial flowering parts, collected during two different years, were obtained by hydrodistillation and analyzed by gas chromatography - mass spectrometry. Forty-five compon...

Chemical composition and antibacterial activity of the essential oil from Mentha requienii Bentham.

Nat. Prod. Res. 27(2) , 93-9, (2013)

The chemical composition of essential oil obtained by hydrodistillation of the fresh aerial parts of Mentha requienii Bentham (Lamiaceae) collected on the Gennargentu Mountains (Sardinia, Italy) has been investigated by gas chromatography and gas chromatograp...

In vitro production of M. × piperita not containing pulegone and menthofuran.

Acta Biochim. Pol. 59(3) , 417-23, (2012)

The essential oils (EOs) and static headspaces (HSs) of in vitro plantlets and callus of Mentha x piperita were characterized by GC-MS analysis. Leaves were used as explants to induce in vitro plant material. The EO yields of the in vitro biomass were much lo...

GC-MS analysis of Ziziphora clinopodioides essential oil from North Xinjiang, China.

Nat. Prod. Commun. 7(1) , 81-2, (2012)

The essential oils of Ziziphora clinopodioide Lam. from four different production areas (Banfang ditch; Altay mountains; Tuoli; Terks) were investigated. The oils were extracted by hydro-distillation and analyzed by gas chromatography-mass spectrometry (GC-MS...