Methyl 4-formylbenzoate

Methyl 4-formylbenzoate Structure
Methyl 4-formylbenzoate structure
Common Name Methyl 4-formylbenzoate
CAS Number 1571-08-0 Molecular Weight 164.158
Density 1.2±0.1 g/cm3 Boiling Point 265.0±0.0 °C at 760 mmHg
Molecular Formula C9H8O3 Melting Point 59-63 °C(lit.)
MSDS Chinese USA Flash Point 122.5±22.7 °C

Two main metabolites of gentiopicroside detected in rat plasma by LC-TOF-MS following 2,4-dinitrophenylhydrazine derivatization.

J. Pharm. Biomed. Anal. 107 , 1-6, (2015)

The metabolism of gentiopicroside in vivo was studied by LC/MS following 2,4-dinitrophenylhydrazine derivatization for the first time. The ionization efficiency of the major metabolites erythrocentaurin and gentiopicral were greatly enhanced by the new analyt...

New analytical method for the study of metabolism of swertiamarin in rats after oral administration by UPLC-TOF-MS following DNPH derivatization.

Biomed. Chromatogr. 29 , 1184-9, (2015)

The metabolism of swertiamarin in vivo was studied by LC-MS following 2,4-dinitrophenylhydrazine derivatization. The ionization efficiency of the main metabolite erythrocentaurin was greatly enhanced by the new analytical method developed, and erythrocentauri...

Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.

J. Med. Chem. 51 , 5052, (2008)

6-Substituted classical pyrrolo[2,3-d]pyrimidine antifolates with a three- to six-carbon bridge between the heterocycle and the benzoyl-L-glutamate (compounds 2-5, respectively) were synthesized starting from methyl 4-formylbenzoate and a Wittig reaction with...

Organocatalysis by bimacrocyclic NHCs: unexpected formation of a cyclic hemiacetal instead of a gamma-butyrolactone.

Org. Biomol. Chem. 7(3) , 553-6, (2009)

Two bimacrocyclic imidazolinium salts of different size, precursors to respective NHCs (N-heterocyclic carbenes), were tested as precatalysts in the reaction of aromatic aldehydes or ketones with enals. The expected lactones were produced in most cases, but i...