Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-
Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy- structure
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Common Name | Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy- | ||
|---|---|---|---|---|
| CAS Number | 72-43-5 | Molecular Weight | 345.64800 | |
| Density | 1.4 g/cm3 | Boiling Point | greater than or equal to 100ºC. | |
| Molecular Formula | C16H15Cl3O2 | Melting Point | 86-88 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 11 °C | |
| Symbol |
GHS07, GHS08, GHS09 |
Signal Word | Warning | |
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Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
J. Med. Chem. 48 , 5666-74, (2005) We investigated the influence of induced fit of the androgen receptor binding pocket on free energies of ligand binding. On the basis of a novel alignment procedure using flexible docking, molecular dynamics simulations, and linear-interaction energy analysis... |
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A novel fully automated on-line coupled liquid chromatography-gas chromatography technique used for the determination of organochlorine pesticide residues in tobacco and tobacco products.
J. Chromatogr. A. 1374 , 273-7, (2014) In this study, a novel fully automated on-line coupled liquid chromatography-gas chromatography (LC-GC) technique was reported and applied for the determination of organochlorine pesticide residues (OCPs) in tobacco and tobacco products. Using a switching val... |
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Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.
Toxicol. Appl. Pharmacol. 284(1) , 54-64, (2015) Many persistent organic pollutants (POPs) accumulate readily in polar bears because of their position as apex predators in Arctic food webs. The pregnane X receptor (PXR, formally NR1I2, here proposed to be named promiscuous xenobiotic receptor) is a xenobiot... |
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Destruction of halogen-containing pesticides by means of detonation combustion.
Environ. Sci. Pollut. Res. Int. 20(2) , 855-61, (2013) Pesticides that contain a halogen functional group have been destructed by means of detonative combustion. The following compounds were examined: (1) atrazine-2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine-herbicide; (2) bromophos-O,4-bromo-2,5-dichlor... |
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Long-term exposure to organochlorine pesticides and thyroid status in adults in a heavily contaminated area in Brazil.
Environ. Res. 127 , 7-15, (2013) Organochlorine (OC) pesticides are endocrine disruptors altering the thyroid hormonal system. The aim of this study is to investigate the relationship between exposure to OC pesticides and thyroid status in adults from a rural area in Rio de Janeiro, Brazil, ... |
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Prior oral exposure to environmental immunosuppressive chemicals methoxychlor, parathion, or piperonyl butoxide aggravates allergic airway inflammation in NC/Nga mice
Toxicology 309 , 1-8, (2013) • Allergic airway inflammation is aggravated by environmental chemicals methoxychlor, parathion, or piperonylbutoxide. • We investigated the association between immunosuppressive chemicals and development of allergic airway inflammation. • Using an animal mod... |
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In vivo and in vitro effects of the organochlorine pesticides DDT, TCPM, methoxychlor, and lindane on the female reproductive tract of mammals: a review.
Reprod. Toxicol. 25(3) , 316-26, (2008) The present paper summarizes the toxicological data on the effects of the organochlorine pesticides DDT, its metabolites, TCPM, methoxychlor and lindane on folliculogenesis, ovulation, fertilization, and implantation of female reproductive organs in human, la... |
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Neonatal injections of methoxychlor decrease adult rat female reproductive behavior
Neurotoxicology 32(6) , 809-13, (2011) Highlights • Methoxychlor treatment directly to female neonatal rat pups alters reproduction as an adult. • Effects are similar to those caused by estradiol. • Treatment affected both estrus cycle and reproductive behavior. |
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Two-generation reproduction toxicity study in rats with methoxychlor.
Congenit. Anom. (Kyoto.) 52(1) , 28-41, (2012) A two-generation reproduction toxicity study was conducted in rats with a reference estrogenic pesticide, methoxychlor, to validate the sensitivity and competency of current guidelines recommended by the United States Environmental Protection Agency; Japanese... |
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Effect of methoxychlor on Ca(2+) movement and viability in MDCK renal tubular cells.
Basic Clin Pharmacol Toxicol. 111(4) , 224-31, (2012) The effect of the insecticide methoxychlor on the physiology of renal tubular cells is unknown. This study aimed to explore the effect of methoxychlor on cytosolic Ca(2+) concentrations ([Ca(2+) ](i) ) in MDCK renal tubular cells using the Ca(2+) -sensitive f... |