FAK-IN-8

Modify Date: 2024-09-16 17:12:58

FAK-IN-8 structure	Common Name	FAK-IN-8
	CAS Number	1374959-91-7	Molecular Weight	366.22
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₉Cl₂N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FAK-IN-8

FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 µM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1].

Name	FAK-IN-8

Description	FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 µM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK
Target	FAK:5.32 μM (IC50)
In Vitro	FAK-IN-8 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1]. Cell Proliferation Assay[1] Cell Line: MCF-7 and B16-F10 cells Concentration: 0-10 µM Incubation Time: 48 h Result: Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC50 values of 3.57 and 3.52 µM, respectively.
References	[1]. Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.

Molecular Formula	C₁₅H₉Cl₂N₃O₂S
Molecular Weight	366.22