5'-Protected 2,2'-anhydrouridine

Modify Date: 2024-01-12 16:24:16

5'-Protected 2,2'-anhydrouridine structure	Common Name	5'-Protected 2,2'-anhydrouridine
	CAS Number	173170-12-2	Molecular Weight	528.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₈N₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5'-Protected 2,2'-anhydrouridine

5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5'-DMTr-2,2'-anhydrouridine
Synonym	More Synonyms

Description	5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₃₀H₂₈N₂O₇
Molecular Weight	528.55
Exact Mass	528.19000
PSA	101.27000
LogP	3.28850

5'-O-(4,4'-dimethoxytrityl)-2,2'-O-anhydro-1-(β-D-arabinofuranosyl)uracil

2,2'-anhydro-5'-O-(4,4'-dimethoxytrityl)uridine

2,2'-O-anhydro-5'-O-(4,4'-dimethoxytrityl)(β-D-arabinofuranosyl)uracil

2,2'-O-anhydro-1-[5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl]uracil

5'-O-(4,4'-dimethoxytrityl)-2,2'-anhydrouridine

5'-O-dimethoxytrityl anhydrouridine

5'-Protected 2,2'-anhydrouridine

Use of 5'-Protected 2,2'-anhydrouridine

Names

5'-Protected 2,2'-anhydrouridine Biological Activity

Chemical & Physical Properties

Synonyms