BuChE-IN-5

Modify Date: 2024-07-17 11:10:01

BuChE-IN-5 Structure
BuChE-IN-5 structure
Common Name BuChE-IN-5
CAS Number 2402753-39-1 Molecular Weight 377.57
Density N/A Boiling Point N/A
Molecular Formula C25H35N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BuChE-IN-5


BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease[1].

 Names

Name BuChE-IN-5

 BuChE-IN-5 Biological Activity

Description BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease[1].
Related Catalog
Target

Butyrylcholinesterase:1.94 μM (IC50)

References

[1]. Wichur T, et al. 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease. Eur J Med Chem. 2020 Feb 1;187:111916.

 Chemical & Physical Properties

Molecular Formula C25H35N3
Molecular Weight 377.57