HSP90-IN-12

Modify Date: 2024-04-18 19:54:00

HSP90-IN-12 structure	Common Name	HSP90-IN-12
	CAS Number	2408643-60-5	Molecular Weight	400.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HSP90-IN-12

Among vibsanin a analogues, vibsanin a analog C (VAC) showed anti proliferative effect on various cancer cell lines, and the anti proliferative activity was the strongest among vibsanin a analogues. In addition, VAC fluctuated the amount of hsp90 related proteins in cells and inhibited hsp90 mediated protein refolding of luciferase in vitro.

Name	HSP90-IN-12

Description	Among vibsanin a analogues, vibsanin a analog C (VAC) showed anti proliferative effect on various cancer cell lines, and the anti proliferative activity was the strongest among vibsanin a analogues. In addition, VAC fluctuated the amount of hsp90 related proteins in cells and inhibited hsp90 mediated protein refolding of luciferase in vitro.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
References	[1]. Miura K,et al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253.

Molecular Formula	C₂₅H₃₆O₄
Molecular Weight	400.55

HSP90-IN-12

Use of HSP90-IN-12

Names

HSP90-IN-12 Biological Activity

Chemical & Physical Properties