2408643-60-5

2408643-60-5 structure

Name: HSP90-IN-12
Chemical Name: HSP90-IN-12
CAS Number: 2408643-60-5
Molecular Formula: C₂₅H₃₆O₄
Molecular Weight: 400.55
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2022-07-01 16:03:00
Modify Date: 2024-04-18 19:54:00
Among vibsanin a analogues, vibsanin a analog C (VAC) showed anti proliferative effect on various cancer cell lines, and the anti proliferative activity was the strongest among vibsanin a analogues. In addition, VAC fluctuated the amount of hsp90 related proteins in cells and inhibited hsp90 mediated protein refolding of luciferase in vitro.

Name	HSP90-IN-12

Description	Among vibsanin a analogues, vibsanin a analog C (VAC) showed anti proliferative effect on various cancer cell lines, and the anti proliferative activity was the strongest among vibsanin a analogues. In addition, VAC fluctuated the amount of hsp90 related proteins in cells and inhibited hsp90 mediated protein refolding of luciferase in vitro.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
References	[1]. Miura K,et al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253.

Molecular Formula	C₂₅H₃₆O₄
Molecular Weight	400.55