HIV-1 inhibitor-19

Modify Date: 2024-01-09 10:55:26

HIV-1 inhibitor-19 Structure
HIV-1 inhibitor-19 structure
Common Name HIV-1 inhibitor-19
CAS Number 2649837-82-9 Molecular Weight 496.77
Density N/A Boiling Point N/A
Molecular Formula C24H22BClN2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 inhibitor-19


HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively[1].

 Names

Name HIV-1 inhibitor-19

 HIV-1 inhibitor-19 Biological Activity

Description HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively[1].
Related Catalog
References

[1]. Shujing Xu, et al. Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV‑1 non-nucleoside reverse transcriptase inhibitors. Bioorg Med Chem. 2022 Jan 1;53:116531.

 Chemical & Physical Properties

Molecular Formula C24H22BClN2O5S
Molecular Weight 496.77