ATR-IN-18

Modify Date: 2024-01-16 08:46:45

ATR-IN-18 structure	Common Name	ATR-IN-18
	CAS Number	2766407-55-8	Molecular Weight	517.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₂F₃N₇O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ATR-IN-18

ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity[1].

Name	ATR-IN-18

Description	ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR
Target	ATR:0.69 nM (IC50)
References	[1]. Xiaohui Liu, et al. Triheterocyclic derivative, and pharmaceutical composition and application thereof. WO2022078480A1.

Molecular Formula	C₁₉H₂₂F₃N₇O₅S
Molecular Weight	517.48

ATR-IN-18

Use of ATR-IN-18

Names

ATR-IN-18 Biological Activity

Chemical & Physical Properties