ATR-IN-4

Modify Date: 2024-01-09 13:14:35

ATR-IN-4 Structure
ATR-IN-4 structure
Common Name ATR-IN-4
CAS Number 2574545-45-0 Molecular Weight 364.40
Density N/A Boiling Point N/A
Molecular Formula C18H20N8O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ATR-IN-4


ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor. ATR-IN-4 inhibits growth of human prostate cancer cells DU145 and human lung cancer cells NCI-H460 with IC50s of 130.9 nM and 41 .33 nM, respectively. (Patent CN112142744A, compound 13)[1].

 Names

Name ATR-IN-4

 ATR-IN-4 Biological Activity

Description ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor. ATR-IN-4 inhibits growth of human prostate cancer cells DU145 and human lung cancer cells NCI-H460 with IC50s of 130.9 nM and 41 .33 nM, respectively. (Patent CN112142744A, compound 13)[1].
Related Catalog
References

[1]. Substituted fused heteroaromatic bicyclic compounds as kinase inhibitors and uses thereof. CN112142744A.

 Chemical & Physical Properties

Molecular Formula C18H20N8O
Molecular Weight 364.40