2'-Deoxy-2'-fluorouridine

Modify Date: 2024-01-12 01:28:07

2'-Deoxy-2'-fluorouridine Structure
2'-Deoxy-2'-fluorouridine structure
Common Name 2'-Deoxy-2'-fluorouridine
CAS Number 362049-50-1 Molecular Weight 246.192
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H9D2FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Deoxy-2'-fluorouridine


2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine[1]. 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis[2].

 Names

Name 2'-fluorodeoxyuridine-5,6-d2
Synonym More Synonyms

 2'-Deoxy-2'-fluorouridine Biological Activity

Description 2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine[1]. 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. J V Tuttle, et al. Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents. J Med Chem  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C9H9D2FN2O5
Molecular Weight 246.192
Exact Mass 246.065201
PSA 104.55000
LogP -1.31
Index of Refraction 1.608

 Synonyms

2'-Deoxy-2'-fluorouridine
Uridine, 2'-deoxy-2'-fluoro-
2'-Fluoro-2'-deoxyuridine