Doxifluridine-d2
Modify Date: 2024-01-31 17:47:28
Doxifluridine-d2 structure
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Common Name | Doxifluridine-d2 | ||
|---|---|---|---|---|
| CAS Number | 84258-25-3 | Molecular Weight | 248.205 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H9D2FN2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Doxifluridine-d2Doxifluridine-d2 is the deuterium labeled Doxifluridine[1]. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. |
| Name | 1-[5-(dideuteriomethyl)-3,4-dihydroxyoxolan-2-yl]-5-fluoropyrimidine-2,4-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Doxifluridine-d2 is the deuterium labeled Doxifluridine[1]. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C9H9D2FN2O5 |
| Molecular Weight | 248.205 |
| Exact Mass | 248.077759 |
| PSA | 104.55000 |
| LogP | -0.96 |
| Index of Refraction | 1.605 |
| 1-{5-[(5,5-H)Deoxy]-β-D-glycero-pentofuranosyl}-5-fluoro-2,4(1H,3H)-pyrimidinedione |
| Doxifluridine-d2 |
| 2,4(1H,3H)-Pyrimidinedione, 1-[5-(deoxy-5,5-d)-β-D-glycero-pentofuranosyl]-5-fluoro- |