5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine

Modify Date: 2024-02-05 16:06:47

5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine Structure
5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine structure
Common Name 5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine
CAS Number 89128-99-4 Molecular Weight 399.34
Density N/A Boiling Point N/A
Molecular Formula C13H16F3N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine


5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-N-methyl-N-TFA-aminomethyl-2-thiouridine
Synonym More Synonyms

  Biological Activity

Description 5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C13H16F3N3O6S
Molecular Weight 399.34
Exact Mass 399.07100
PSA 160.11000

 Synonyms

N-[1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl]-2,2,2-trifluoro-N-methyl-acetamide
N-methyl-N-TFA-aminomethyl-2-thiouridine