holo-transferrin

Names

[ Name ]:
holo-transferrin

[Synonym ]:
EINECS 234-318-8
MFCD00130536

Biological Activity

[Description]:

Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrins can bind to and mediate the transport of iron[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

Transferrin receptor[1]

[In Vitro]

Transferrins (0.2, 1 and 5 μM, 30 min) enhances the enzymatic activity of thrombin[2]. Transferrins (0.2, 1 and 5 μM, 30 min) enhances the ability of thrombin and FXIIa to hydrolyze their natural substrates (fibrinogen)[2]. Transferrins can conjugate with cytochrome c, the conjugates can be uptaken by transferrin receptor overexpressing A549 cells, thereby inducing cell death[3].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₂N₆O₄

[ Molecular Weight ]:
362.38368

[ Appearance of Characters ]:
powder

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 50 mg/mL | Soluble in water (50 mg/ml).

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
B,Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

LipiD-QuanT: a novel method to quantify lipid accumulation in live cells.

J. Lipid Res. 56 , 2206-16, (2015)

Lipid droplets (LDs) are the main storage organelles for triglycerides. Elucidation of lipid accumulation mechanisms and metabolism are essential to understand obesity and associated diseases. Adipoge...

Differentiation potential of o bombay human-induced pluripotent stem cells and human embryonic stem cells into fetal erythroid-like cells.

Cell J. 16(4) , 426-39, (2015)

There is constant difficulty in obtaining adequate supplies of blood components, as well as disappointing performance of "universal" red blood cells. Advances in somatic cell reprogramming of human-in...

Streptococcus pneumoniae secretes a glyceraldehyde-3-phosphate dehydrogenase, which binds haemoglobin and haem.

Biometals 27(4) , 683-93, (2014)

Streptococcus pneumoniae is a gram positive encapsulated bacterium responsible of septicaemia and upper respiratory infections in children. This pathogen requires iron to survive in the host, which it...