Name | 1,1,2,2,2-pentadeuterioethyl (3R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate |
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Description | Oseltamivir-d5 is the deuterium labeled Oseltamivir[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50 of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2]. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Molecular Formula | C16H23D5N2O4 |
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Molecular Weight | 317.43500 |
Exact Mass | 317.23600 |
PSA | 94.14000 |
LogP | 2.82600 |