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98665-19-1

98665-19-1 structure
98665-19-1 structure
  • Name: Ganoderic acid H
  • Chemical Name: (2R,6S)-6-[(3S,5R,10S,12S,13R,14R,17R)-12-acetyloxy-3-hydroxy-4,4,10,13,14-pentamethyl-7,11,15-trioxo-1,2,3,5,6,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
  • CAS Number: 98665-19-1
  • Molecular Formula: C32H44O9
  • Molecular Weight: 572.69
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-03-25 08:00:00
  • Modify Date: 2024-01-03 17:41:39
  • Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling[1].

Name (2R,6S)-6-[(3S,5R,10S,12S,13R,14R,17R)-12-acetyloxy-3-hydroxy-4,4,10,13,14-pentamethyl-7,11,15-trioxo-1,2,3,5,6,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
Synonyms Ganoderic acid H
Description Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling[1].
Related Catalog
References

[1]. Jiang J, et al. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med. 2008 May;21(5):577-84.

Density 1.25g/cm3
Boiling Point 710ºC at 760 mmHg
Melting Point 155-156 °C
Molecular Formula C32H44O9
Molecular Weight 572.69
Flash Point 222.5ºC
PSA 152.11000
LogP 3.63530
Index of Refraction 1.557
Water Solubility Insuluble (2.6E-3 g/L) (25 ºC)