6068-78-6
6068-78-6 structure
- Name: 3',4'-Dihydroxyflavonol
- Chemical Name: 2-(3,4-dihydroxyphenyl)-3-hydroxychromen-4-one
- CAS Number: 6068-78-6
- Molecular Formula: C15H10O5
- Molecular Weight: 270.24
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2018-08-13 20:12:28
- Modify Date: 2024-01-02 11:47:03
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3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1].
| Name | 2-(3,4-dihydroxyphenyl)-3-hydroxychromen-4-one |
|---|---|
| Synonyms |
3',4'-dihydroxyflavonol
3',4'-Dihydroxyflavonol 3,3',4'-TRIHYDROXYFLAVONE 3,3',4'-trihydroxyflavon 2-(3,4-dihydroxy-phenyl)-3-hydroxy-chromen-4-one |
| Description | 3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1]. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized third-order branches of rat mesenteric arteries[2]. |
| References |
| Density | 1.579g/cm3 |
|---|---|
| Boiling Point | 508.9ºC at 760 mmHg |
| Molecular Formula | C15H10O5 |
| Molecular Weight | 270.24 |
| Flash Point | 198ºC |
| Exact Mass | 270.05300 |
| PSA | 90.90000 |
| LogP | 2.57680 |
| Index of Refraction | 1.747 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2914501900 |
|
~69%
6068-78-6 |
| Literature: Van Acker; Hageman; Haenen; Van der Vijgh; Bast; Menge Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3752 - 3760 |
|
~%
6068-78-6 |
| Literature: Van Acker; Hageman; Haenen; Van der Vijgh; Bast; Menge Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3752 - 3760 |
|
~%
6068-78-6 |
| Literature: Van Acker; Hageman; Haenen; Van der Vijgh; Bast; Menge Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3752 - 3760 |
|
~%
6068-78-6 |
| Literature: Van Acker; Hageman; Haenen; Van der Vijgh; Bast; Menge Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3752 - 3760 |
|
~45%
6068-78-6 |
| Literature: Sobottka; Werner; Blaschke; Kiefer; Nowe; Dannhardt; Schapoval; Schenkel; Scriba Archiv der Pharmazie, 2000 , vol. 333, # 7 p. 205 - 210 |
|
~%
6068-78-6 |
| Literature: Sobottka; Werner; Blaschke; Kiefer; Nowe; Dannhardt; Schapoval; Schenkel; Scriba Archiv der Pharmazie, 2000 , vol. 333, # 7 p. 205 - 210 |
|
~%
6068-78-6 |
| Literature: Sobottka; Werner; Blaschke; Kiefer; Nowe; Dannhardt; Schapoval; Schenkel; Scriba Archiv der Pharmazie, 2000 , vol. 333, # 7 p. 205 - 210 |
| Precursor 6 | |
|---|---|
| DownStream 0 | |
| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |