52940-48-4

52940-48-4 structure

Name: 9H-Purine,6-(4-morpholinyl)-9-b-D-ribofuranosyl-
Chemical Name: 2-(hydroxymethyl)-5-(6-morpholin-4-ylpurin-9-yl)oxolane-3,4-diol
CAS Number: 52940-48-4
Molecular Formula: C₁₄H₁₉N₅O₅
Molecular Weight: 337.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-05-08 14:01:54
Modify Date: 2024-01-16 18:22:50
6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-(hydroxymethyl)-5-(6-morpholin-4-ylpurin-9-yl)oxolane-3,4-diol
Synonyms	6-(morpholin-4-yl)-9-pentofuranosyl-9H-purine 6-morpholinopurine riboside

Description	6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

110-91-8

927818-53-9

~58%

52940-48-4

Literature: Bae, Suyeal; Lakshman, Mahesh K. Journal of the American Chemical Society, 2009 , vol. 131, # 49 p. 17993 - 17993

58-63-9

52940-48-4

385806-18-8

52940-48-4

Literature: Lin, Xiaoyu; Robins, Morris J. Organic Letters, 2000 , vol. 2, # 22 p. 3497 - 3499

3181-38-2

52940-48-4

Literature: Lin, Xiaoyu; Robins, Morris J. Organic Letters, 2000 , vol. 2, # 22 p. 3497 - 3499

110-91-8

2004-06-0

52940-48-4