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78439-06-2

78439-06-2 structure
78439-06-2 structure
  • Name: Ceftazidime Pentahydrate
  • Chemical Name: ceftazidime pentahydrate
  • CAS Number: 78439-06-2
  • Molecular Formula: C22H32N6O12S2
  • Molecular Weight: 546.576
  • Catalog: API Antibiotics Cephalosporin
  • Create Date: 2018-03-28 08:00:00
  • Modify Date: 2024-01-04 18:33:35
  • Ceftazidime pentahydrate (GR20263 pentahydrate) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1].

Name ceftazidime pentahydrate
Synonyms MFCD00153936
EINECS 276-715-9
Pyridinium, 1-[[(6R,7R)-7-[[2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
(6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Ceftazidime
Description Ceftazidime pentahydrate (GR20263 pentahydrate) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1].
Related Catalog
References

[1]. Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29(2):105-61.

Melting Point >150ºC(dec.)
Molecular Formula C22H32N6O12S2
Molecular Weight 546.576
Exact Mass 546.099121
PSA 244.76000
LogP -2.84
Storage condition 2-8°C
Hazard Codes Xn: Harmful;
Risk Phrases R42/43
Safety Phrases 22-36/37-45-37-24
RIDADR NONH for all modes of transport
WGK Germany 1
HS Code 2941905990
HS Code 2941905990