30408-30-1

30408-30-1 structure

Name: NSC 613948
Chemical Name: 8-(Hydroxymethyl)-6,11-dimethyl-4H-[1,3]oxazolo[5,4,3-ij]pyrido[3 ,2-g]quinoline-4,10(11H)-dione
CAS Number: 30408-30-1
Molecular Formula: C₁₆H₁₄N₂O₄
Molecular Weight: 298.29300
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-01-19 11:57:25
Modify Date: 2024-01-05 18:53:56
Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].

Name	8-(Hydroxymethyl)-6,11-dimethyl-4H-[1,3]oxazolo[5,4,3-ij]pyrido[3 ,2-g]quinoline-4,10(11H)-dione
Synonyms	8-(hydroxymethyl)-3,7-dimethyl-3,7-dihydro-1h-purine-2,6-dione 8-Hydroxymethyl-theobromin 8-Hydroxymethyl-3,7-dimethyl-3,7-dihydro-purin-2,6-dion 8-Hydroxymethyl-6,11-dimethyl-11H-oxazolo[5,4,3-ij]pyrido[3,2-g]chinolin-4,10-dion 8-hydroxymethyl-3,7-dimethyl-3,7-dihydro-purine-2,6-dione 8-Hydroxymethyltheobromine 8-hydroxymethyl-6,11-dimethyl-11H-oxazolo[5,4,3-ij]pyrido[3,2-g]quinoline-4,10-dione

Description	Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Strelitz F, et, al. NYBOMYCIN, A NEW ANTIBIOTIC WITH ANTIPHAGE AND ANTIBACTERIAL PROPERTIES. Proc Natl Acad Sci U S A. 1955 Sep 15;41(9):620-4. [2]. Arai M, et, al. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg Med Chem. 2015 Jul 1;23(13):3534-41.

35982-88-8

30408-30-1

Literature: Forbis,R.M.; Rinehart,K.L. Journal of the American Chemical Society, 1973 , vol. 95, p. 5003 - 5013