NSC 613948

Modify Date: 2024-01-05 18:53:56

NSC 613948 Structure
NSC 613948 structure
Common Name NSC 613948
CAS Number 30408-30-1 Molecular Weight 298.29300
Density 1.54g/cm3 Boiling Point 538.7ºC at 760 mmHg
Molecular Formula C16H14N2O4 Melting Point N/A
MSDS N/A Flash Point 279.6ºC

 Use of NSC 613948


Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].

 Names

Name 8-(Hydroxymethyl)-6,11-dimethyl-4H-[1,3]oxazolo[5,4,3-ij]pyrido[3 ,2-g]quinoline-4,10(11H)-dione
Synonym More Synonyms

 NSC 613948 Biological Activity

Description Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].
Related Catalog
References

[1]. Strelitz F, et, al. NYBOMYCIN, A NEW ANTIBIOTIC WITH ANTIPHAGE AND ANTIBACTERIAL PROPERTIES. Proc Natl Acad Sci U S A. 1955 Sep 15;41(9):620-4.

[2]. Arai M, et, al. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg Med Chem. 2015 Jul 1;23(13):3534-41.

 Chemical & Physical Properties

Density 1.54g/cm3
Boiling Point 538.7ºC at 760 mmHg
Molecular Formula C16H14N2O4
Molecular Weight 298.29300
Flash Point 279.6ºC
Exact Mass 298.09500
PSA 73.46000
LogP 1.00400
Vapour Pressure 1.95E-12mmHg at 25°C
Index of Refraction 1.737

 Synonyms

8-(hydroxymethyl)-3,7-dimethyl-3,7-dihydro-1h-purine-2,6-dione
8-Hydroxymethyl-theobromin
8-Hydroxymethyl-3,7-dimethyl-3,7-dihydro-purin-2,6-dion
8-Hydroxymethyl-6,11-dimethyl-11H-oxazolo[5,4,3-ij]pyrido[3,2-g]chinolin-4,10-dion
8-hydroxymethyl-3,7-dimethyl-3,7-dihydro-purine-2,6-dione
8-Hydroxymethyltheobromine
8-hydroxymethyl-6,11-dimethyl-11H-oxazolo[5,4,3-ij]pyrido[3,2-g]quinoline-4,10-dione
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