149904-87-0

149904-87-0 structure
149904-87-0 structure
  • Name: CP 86325 sodium salt
  • Chemical Name: sodium,5-[[4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl]methyl]-1,3-thiazolidin-3-ide-2,4-dione
  • CAS Number: 149904-87-0
  • Molecular Formula: C23H19N2NaO4S
  • Molecular Weight: 442.46300
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
  • Create Date: 2016-07-13 05:16:29
  • Modify Date: 2024-01-04 20:23:48
  • Darglitazone Sodium, a thiazolidinedione, is an orally active, potent, and selective PPAR-γ (peroxisome proliferator-activated receptor) agonist. Darglitazone Sodium is effective in controlling blood glucose and lipid metabolism, and can be used for type II diabetes research[1][2].

Name sodium,5-[[4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl]methyl]-1,3-thiazolidin-3-ide-2,4-dione
Synonyms Darglitazone sodium salt
DARGLITAZONE SODIUM
UNII-A1P35HS4XI
CP-86,325-2
Description Darglitazone Sodium, a thiazolidinedione, is an orally active, potent, and selective PPAR-γ (peroxisome proliferator-activated receptor) agonist. Darglitazone Sodium is effective in controlling blood glucose and lipid metabolism, and can be used for type II diabetes research[1][2].
Related Catalog
Target

PPAR-γ

References

[1]. Rashmi Kumari, et al. The PPAR-gamma agonist, darglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse. J Cereb Blood Flow Metab. 2010 Feb;30(2):352-60.

[2]. Hoenig M, Ferguson DC. Effect of darglitazone on glucose clearance and lipid metabolism in obese cats. Am J Vet Res. 2003 Nov;64(11):1409-13.

Molecular Formula C23H19N2NaO4S
Molecular Weight 442.46300
Exact Mass 442.09600
PSA 120.89000
LogP 4.50800
RIDADR NONH for all modes of transport