93673-82-6

93673-82-6 structure
93673-82-6 structure
  • Name: Hydroxy-PEG1-C2-methyl ester
  • Chemical Name: methyl 3-(2-hydroxyethoxy)propanoate
  • CAS Number: 93673-82-6
  • Molecular Formula: C6H12O4
  • Molecular Weight: 148.15700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-04-21 06:35:44
  • Modify Date: 2024-01-12 11:20:59
  • Hydroxy-PEG1-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name methyl 3-(2-hydroxyethoxy)propanoate
Description Hydroxy-PEG1-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H12O4
Molecular Weight 148.15700
Exact Mass 148.07400
PSA 55.76000